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[新型冠状病毒肺炎重症及危重症患者的药学服务]

[Pharmaceutical care for severe and critically ill patients with COVID-19].

作者信息

Jiang Saiping, Li Lu, Ru Renping, Zhang Chunhong, Rao Yuefeng, Lin Bin, Wang Rongrong, Chen Na, Wang Xiaojuan, Cai Hongliu, Sheng Jifang, Zhou Jianying, Lu Xiaoyang, Qiu Yunqing

机构信息

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Hangzhou Xixi Hospital, Hangzhou 310023, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(2):158-169. doi: 10.3785/j.issn.1008-9292.2020.03.01.

Abstract

Severe and critically ill patients with coronavirus disease 2019 (COVID-19) were usually with underlying diseases, which led to the problems of complicated drug use, potential drug-drug interactions and medication errors in special patients. Based on ( 6), and -19: , we summarized the experience in the use of antiviral drugs, corticosteroids, vascular active drugs, antibacterial, probiotics, nutrition support schemes in severe and critically ill COVID-19 patients. It is also suggested to focus on medication management for evaluation of drug efficacy and duration of treatment, prevention and treatment of adverse drug reactions, identification of potential drug-drug interactions, individualized medication monitoring based on biosafety protection, and medication administration for special patients.

摘要

新型冠状病毒肺炎(COVID-19)重症和危重症患者通常伴有基础疾病,这导致特殊患者存在用药复杂、潜在药物相互作用及用药错误等问题。基于(6)以及-19:,我们总结了重症和危重症COVID-19患者使用抗病毒药物、糖皮质激素、血管活性药物、抗菌药物、益生菌、营养支持方案的经验。还建议重点关注药物管理,以评估药物疗效和治疗时长、预防和治疗药物不良反应、识别潜在药物相互作用、基于生物安全保护进行个体化用药监测以及特殊患者的给药。

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本文引用的文献

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Antibiotic Dosing in Continuous Renal Replacement Therapy.连续肾脏替代治疗中的抗生素剂量。
Adv Chronic Kidney Dis. 2017 Jul;24(4):219-227. doi: 10.1053/j.ackd.2017.05.004.
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Therapeutic drug monitoring of anti-infective agents in critically ill patients.危重症患者抗感染药物的治疗药物监测
Expert Rev Clin Pharmacol. 2016 Jul;9(7):961-79. doi: 10.1586/17512433.2016.1172209. Epub 2016 Apr 15.

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