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[感染性脊柱炎的神经根及类神经根综合征及其鉴别诊断意义]

[The radicular and pseudoradicular syndrome of infectious spondylitis and its differential diagnostic significance].

作者信息

Weber M, Ernst H U

机构信息

Abteilung Orthopädie im Zentrum Chirurgie des Klinikums der Albert-Ludwigs-Universität Freiburg.

出版信息

Z Orthop Ihre Grenzgeb. 1988 Sep-Oct;126(5):563-9. doi: 10.1055/s-2008-1044484.

DOI:10.1055/s-2008-1044484
PMID:3239179
Abstract

Infectious spondylitis is now the most common form of hematogenous osteomyelitis. In 37% of patients followed up it causes root irritation without peripheral paralysis, and radicular and pseudoradicular syndromes. Accounting for 8.2% of the cases, incomplete paraplegias are not as rare as is usually assumed. In certain sections of the spine infectious spondylitis is encountered very frequently (T7/8, T9/10, L3/4, and L4/5). The distribution pattern of the paralyses does not correspond to the frequency of the spondylitis in the individual segments of the spine. Radicular syndromes are more common in the lumbar spine, incomplete paraplegias in the thoracic spine. The neurologic risk depends on the patient's age: while very low in children, it is distinctly higher in patients aged over 70. Only the paraplegia risk is dependent on the extent of vertebral destruction. This in turn depends on the time that elapses until diagnosis. Almost all cases of spondylitis are still diagnosed unnecessarily late. Radicular and pseudoradicular symptoms accelerate diagnosis of spondylitis. Inflammatory and mechanical factors cause the radicular and pseudoradicular syndromes. Detection by radiologic examination is not usually possible. As regards formal pathogenesis, degenerative and inflammatory vertebragenous syndromes are indistinguishable, and spondylitis can only be clinically recognized from its general symptoms. No signs of paralysis occurred in any of the patients in whom spondylitis had been diagnosed in good time. Therefore, spondylitis diagnosis must also be improved in order to prevent neurologic complications.

摘要

感染性脊柱炎是目前血源性骨髓炎最常见的形式。在37%接受随访的患者中,它会导致神经根刺激但无周围性麻痹,以及神经根性和假性神经根性综合征。不完全性截瘫占病例的8.2%,并不像通常认为的那样罕见。在脊柱的某些节段,感染性脊柱炎非常常见(胸7/8、胸9/10、腰3/4和腰4/5)。麻痹的分布模式与脊柱各节段脊柱炎的发生频率并不对应。神经根性综合征在腰椎更常见,不完全性截瘫在胸椎更常见。神经风险取决于患者年龄:儿童中风险很低,而70岁以上患者则明显更高。只有截瘫风险取决于椎体破坏的程度。而这又取决于直到诊断时所经过的时间。几乎所有脊柱炎病例的诊断仍然不必要地延迟。神经根性和假性神经根性症状会加速脊柱炎的诊断。炎症和机械因素导致神经根性和假性神经根性综合征。通常无法通过放射学检查发现。就正式的发病机制而言,退行性和炎症性脊椎源性综合征难以区分,脊柱炎只能从其一般症状进行临床识别。在及时诊断出脊柱炎的患者中,没有任何患者出现麻痹迹象。因此,为了预防神经并发症,也必须改进脊柱炎的诊断。

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New inflammation markers for early detection of spondylodiscitis.用于早期检测脊椎 discsitis 的新炎症标志物。
Eur Spine J. 1992 Dec;1(3):152-5. doi: 10.1007/BF00301305.