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[滑膜印片细胞学中风湿性疾病局部炎症活动的反映]

[Reflection of local inflammatory activity in rheumatic diseases in synovial imprint cytology].

作者信息

Schwenke R, Heidelmann G

机构信息

Rheumadispensaire der Funktionseinheit Stadtkrankenhaus, Dr. Paul Kirchner/Poliklinik Radeberg, Medizinischen Akademie, Carl Gustav Carus, Dresden, DDR.

出版信息

Z Rheumatol. 1988 Sep-Oct;47(5):329-32.

PMID:3239262
Abstract

Cytological signs of the synovial imprint preparation have been correlated with findings of systemic, histomorphologic and arthroscopic inflammatory symptoms in 123 patients with rheumatic arthropathies. Out of the observed cellular and non-cellular structures of the synovial imprint cytology, fibrin, fibrinous necroses and relations of neutrophil polymorphs, as well as synovial phagocytes, reflect the acute inflammatory activity of the joint examined. The content in synovial imprint preparation of cells and cell groups are manners of expression both of the acute and proliferative activity as well as basic activity, respectively, of the synovial membrane. The synovial imprint cytogram's number of giant cells correlates with the histomorphologic degree of severity of the local proliferative inflammatory activity. Correlations between the level of the 1-h-value of the erythrocyte sedimentation rate (ESR) and the imprintocytological finding cellular distribution density, as well as relations between synoviocytes and neutrophil polymorphs, had to be demonstrated statistically. No correlations, however, were found between cytologic structures of inflammatory activities of the synovial imprint cytogram and the differential cell picture of the associated serosynovitis.

摘要

滑膜印片标本的细胞学特征已与123例风湿性关节病患者的全身、组织形态学及关节镜检查的炎症表现相关联。在滑膜印片细胞学观察到的细胞和非细胞结构中,纤维蛋白、纤维蛋白坏死以及中性多形核白细胞和滑膜吞噬细胞的关系,反映了所检查关节的急性炎症活动。滑膜印片标本中细胞和细胞群的含量分别是滑膜急性、增殖性及基础活性的表达方式。滑膜印片细胞图中巨细胞的数量与局部增殖性炎症活动的组织形态学严重程度相关。红细胞沉降率(ESR)1小时值水平与印片细胞学发现的细胞分布密度之间的相关性,以及滑膜细胞与中性多形核白细胞之间的关系,必须进行统计学论证。然而,滑膜印片细胞图炎症活动的细胞学结构与相关浆液性滑膜炎的细胞分类图之间未发现相关性。

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