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急诊科肺栓塞临床决策规则的应用:一项回顾性研究。

The use of clinical decision rules for pulmonary embolism in the emergency department: a retrospective study.

作者信息

Al Dandan Omran, Hassan Ali, Alnasr Afnan, Al Gadeeb Mohammed, AbuAlola Hossain, Alshahwan Sarah, Al Shammari Malak, Alzaki Alaa

机构信息

Department of Radiology, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Al-Khobar, Saudi Arabia.

Department of Family and Community Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

Int J Emerg Med. 2020 May 11;13(1):23. doi: 10.1186/s12245-020-00281-1.

DOI:10.1186/s12245-020-00281-1
PMID:32393324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7216540/
Abstract

BACKGROUND

Pulmonary embolism (PE) is a common and life-threatening medical condition with non-specific clinical presentation. Computed tomography pulmonary angiography (CT-PA) has been the diagnostic modality of choice, but its use is not without risks. Clinical decision rules have been established for the use of diagnostic modalities for patients with suspected PE. This study aims to assess the adherence of physicians to the diagnostic algorithms and rules.

METHODS

A retrospective observational study examining the utilization of CT-PA in the Emergency Department of King Fahd Hospital of Imam Abdulrahman Bin Faisal University for patients with suspected PE from May 2016 to December 2019. The electronic health records were used to collect the data, including background demographic data, clinical presentation, triage vital signs, D-dimer level (if ordered), risk factors for PE, and the CT-PA findings. The Wells score and pulmonary embolism rule-out (PERC) criteria were calculated retrospectively without knowledge of the results of D-dimer and the CT-PA.

RESULTS

The study involved a total of 353 patients (125 men and 228 women) with a mean age of 46.7 ± 18.4 years. Overall, 200 patients (56.7%) were classified into the "PE unlikely" group and 153 patients (43.3%) in the "PE likely" group as per Wells criteria. Out of all the CT-PA, 119 CT-PA (33.7%) were requested without D-dimer assay (n = 114) or with normal D-dimer level (n = 5) despite being in the "PE unlikely" group. Only 49 patients had negative PERC criteria, of which three patients had PE.

CONCLUSIONS

The study revealed that approximately one-third of all CT-PA requests were not adhering to the clinical decision rules with a significant underutilization of D-dimer assay in such patients. To reduce overutilization of imaging, planned interventions to promote the adherence to the current guidelines seem imperative.

摘要

背景

肺栓塞(PE)是一种常见且危及生命的疾病,临床表现不具有特异性。计算机断层扫描肺动脉造影(CT-PA)一直是首选的诊断方式,但使用它并非没有风险。已为疑似PE患者制定了诊断方式的临床决策规则。本研究旨在评估医生对诊断算法和规则的遵循情况。

方法

一项回顾性观察研究,调查了2016年5月至2019年12月期间在伊玛目阿卜杜勒拉赫曼·本·费萨尔大学法赫德国王医院急诊科对疑似PE患者使用CT-PA的情况。利用电子健康记录收集数据,包括背景人口统计学数据、临床表现、分诊生命体征、D-二聚体水平(若已检测)、PE危险因素以及CT-PA检查结果。在不了解D-二聚体和CT-PA结果的情况下,回顾性计算Wells评分和肺栓塞排除(PERC)标准。

结果

该研究共纳入353例患者(125例男性和228例女性),平均年龄为46.7±18.4岁。总体而言,根据Wells标准,200例患者(56.7%)被归类为“PE可能性低”组,153例患者(43.3%)被归类为“PE可能性高”组。在所有CT-PA检查中,尽管处于“PE可能性低”组,但仍有119例CT-PA(33.7%)在未进行D-二聚体检测(n = 114)或D-二聚体水平正常(n = 5)的情况下被要求进行。只有49例患者符合PERC阴性标准,其中三例患者患有PE。

结论

该研究表明,所有CT-PA检查申请中约有三分之一未遵循临床决策规则,且此类患者中D-二聚体检测的利用率显著不足。为减少影像学检查的过度使用,采取有计划的干预措施以促进对现行指南的遵循似乎势在必行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9416/7216540/16f09022a20a/12245_2020_281_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9416/7216540/16f09022a20a/12245_2020_281_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9416/7216540/16f09022a20a/12245_2020_281_Fig1_HTML.jpg

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