ATP 响应性漆酶@ZIF-90 作为信号放大平台，实现大鼠脑组织中 ATP 的间接高灵敏在线检测。
ATP-responsive laccase@ZIF-90 as a signal amplification platform to achieve indirect highly sensitive online detection of ATP in rat brain.
机构信息
Department of Chemistry, Capital Normal University, Beijing, 100048, China.
出版信息
Chem Commun (Camb). 2020 Jun 11;56(47):6436-6439. doi: 10.1039/d0cc02021d.
PMID:32393954
Abstract
A novel electrochemical online system for indirect, highly sensitive and selective online monitoring of ATP in the cerebral microdialysate is presented based on the particular reaction of ATP with zeolitic imidazole framework-90 (ZIF-90) encapsulated laccase microcrystals (laccase@ZIF-90) and the natural catalytic activity of laccase.
摘要
提出了一种新颖的电化学在线系统，用于间接、高灵敏度和选择性地在线监测脑微透析液中的 ATP，该系统基于 ATP 与封装在沸石咪唑骨架-90（ZIF-90）中的漆酶微晶体（laccase@ZIF-90）的特殊反应以及漆酶的天然催化活性。
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