Department of Critical Care Nursing, College of Nursing, Qassim University, Buraydah, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2020 Mar-Apr;31(2):320-334. doi: 10.4103/1319-2442.284006.
Peritonitis is associated with an increasing morbidity and mortality rate in peritoneal dialysis patients. A number of peritonitis cases result in hypoalbuminemia, and in other cases, peritonitis follows a decline in the serum albumin level. However, it is not clear whether the level of serum albumin can be utilized to predict and prevent the incidence of peritonitis. A quasi-systematic search of the literature was conducted in the following databases: Cochrane, EBSCO, ProQuest, AHMED, CINHAL, MEDLINE, and EMBASE, from January 2008 to January 2018. The data was reviewed and extracted from each study. The quality of the studies was assessed using the Critical Appraisal Skills Programme and the Newcastle-Ottawa Scale. Six articles met the stated inclusion criteria of the quasi-systematic review. The study found a significant correlation between a low serum albumin level at the start of continuous ambulatory peritoneal dialysis (CAPD) and the development of peritonitis. Thus, hypoalbuminemia can be utilized as a warning sign of the occurrence of peritonitis in CAPD. Consequently, immediate intervention is required when the level of serum albumin declines in order to prevent peritonitis.
腹膜炎与腹膜透析患者的发病率和死亡率增加有关。许多腹膜炎病例导致低白蛋白血症，而在其他情况下，腹膜炎后血清白蛋白水平下降。然而，目前尚不清楚血清白蛋白水平是否可用于预测和预防腹膜炎的发生。从 2008 年 1 月至 2018 年 1 月，我们在以下数据库中进行了半系统检索：Cochrane、EBSCO、ProQuest、AHMED、CINHAL、MEDLINE 和 EMBASE。对每项研究的数据进行了审查和提取。使用批判性评估技能计划和纽卡斯尔-渥太华量表评估研究质量。六篇文章符合半系统综述的既定纳入标准。研究发现，开始持续非卧床腹膜透析（CAPD）时血清白蛋白水平低与腹膜炎的发生有显著相关性。因此，低白蛋白血症可用作 CAPD 发生腹膜炎的警告信号。因此，当血清白蛋白水平下降时，需要立即进行干预，以预防腹膜炎。
