Wood D J, Cooper C, Stevens J, Edwardson J
Department of Orthopaedic Surgery, Leicester Royal Infirmary.
Age Ageing. 1988 Nov;17(6):415-9. doi: 10.1093/ageing/17.6.415.
The relationship between bone mass and dementia in elderly hip fracture patients from areas with different aluminium concentrations in water supplies has been investigated, to determine whether a high concentration of aluminium in the drinking water and the negative calcium balance of age-related osteoporosis together predispose to senile dementia. Mental test scores were recorded on admission to hospital, and Singh indices of radiographs taken at that time assessed blind by a single trained observer. No significant difference in either mental test score (chi 2 = 1.253, df = 2, P = 0.53) or Singh index (chi 2 = 1.039, df = 5, P = 0.96) was found between patients resident in high versus low water aluminum areas. No correlation was detectable between mental test score and Singh index (chi 2 = 0.95, df = 1, P = 0.33).
对来自供水铝浓度不同地区的老年髋部骨折患者的骨量与痴呆症之间的关系进行了调查，以确定饮用水中高浓度的铝和与年龄相关的骨质疏松症的负钙平衡是否共同易患老年痴呆症。入院时记录心理测试分数，并由一名经过培训的观察员对当时拍摄的X光片的辛格指数进行盲法评估。居住在高水铝地区与低水铝地区的患者之间，心理测试分数（卡方 = 1.253，自由度 = 2，P = 0.53）或辛格指数（卡方 = 1.039，自由度 = 5，P = 0.96）均未发现显著差异。心理测试分数与辛格指数之间未检测到相关性（卡方 = 0.95，自由度 = 1，P = 0.33）。
