[应对新型冠状病毒肺炎相关凝血病]
[Dealing with COVID-19-associated coagulopathy].
作者信息
Klok Frederikus A, den Exter Paul L, Huisman Menno V, Eikenboom Jeroen
机构信息
Leids Universitair Medisch Centrum, afd. Trombose en Hemostase, Leiden.
Contact: Frederikus A. Klok (
出版信息
Ned Tijdschr Geneeskd. 2020 Apr 15;164:D5031.
COVID-19 is associated with a high prevalence of activation of the coagulation cascade. It has been suggested that this so-called COVID-19-associated coagulopathy is predictive of a poor outcome and of mortality. Consensus documents on how to manage patients with COVID-19-associated coagulopathy are based on the limited number of mainly retrospective studies that is currently available, and for this reason the recommendations are not always consistent with one another. In this article, we review the first studies into COVID-19-associated coagulopathy and give the most important do's and don'ts for diagnostics and the daily management of coagulopathy and the prevention of complications in patients with, or with strongly-suspected, COVID-19 in Dutch clinical practice.
新冠病毒病（COVID-19）与凝血级联激活的高发生率相关。有人提出，这种所谓的COVID-19相关凝血病可预测不良结局和死亡率。关于如何管理COVID-19相关凝血病患者的共识文件基于目前可用的数量有限的主要为回顾性研究，因此这些建议并不总是相互一致。在本文中，我们回顾了关于COVID-19相关凝血病的首批研究，并给出了荷兰临床实践中针对COVID-19确诊患者或高度疑似患者凝血病诊断、日常管理及并发症预防的最重要的注意事项。
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