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小儿复杂性鼻窦炎的管理模式。

Management Patterns in Pediatric Complicated Sinusitis.

机构信息

The Ohio State University College of Medicine, Columbus, Ohio, USA.

Nationwide Children's Hospital Center for Surgical Outcomes, Columbus, Ohio, USA.

出版信息

Otolaryngol Head Neck Surg. 2020 Oct;163(4):814-821. doi: 10.1177/0194599820918832. Epub 2020 May 12.

Abstract

OBJECTIVES

Sinusitis is a common pediatric illness that can be complicated by periorbital or intracranial extension. Patients can be managed with antimicrobials alone or in conjunction with surgical intervention. This article examines management patterns and outcomes in pediatric patients presenting with complicated sinusitis.

STUDY DESIGN

Case series with chart review.

SETTING

Tertiary care pediatric hospital.

SUBJECTS AND METHODS

An evaluation of 168 pediatric patients with complicated sinusitis with periorbital complications presenting at a single institution from 2008 to 2018 was performed. Demographics, disease characteristics, in-hospital management, and outcomes were recorded and analyzed.

RESULTS

The most common complication was orbital cellulitis, seen in 49% of children. Surgical intervention occurred in 49% of patients, with 36% receiving medical therapy followed by surgery (MTS). Chandler I patients underwent surgical intervention 30% of the time, Chandler II patients 29%, and Chandler III patients 83%. Nineteen percent of initially nonoperative patients started on ampicillin-sulbactam required MTS vs 57% of those started on other antibiotic regimens ( = .01). Twelve percent of initially nonoperative Chandler I to II patients started on ampicillin-sulbactam needed MTS vs 40% started on other antibiotic regimens. Hospital charges for operative patients were $45,056 vs $14,311 for nonoperative patients ( < .01). Hospital charges for patients with surgery followed by medical therapy (SMT) were $45,563 vs $44,393 for MTS ( = .92).

CONCLUSION

Nonoperative early stage patients started on ampicillin-sulbactam had a lower risk of MTS. MTS did not cost significantly more than SMT, and there were no significant outcome differences seen.

摘要

目的

鼻窦炎是一种常见的儿科疾病,可并发眶周或颅内蔓延。患者可单独使用抗菌药物或联合手术干预进行治疗。本文研究了患有复杂鼻窦炎并出现眶周并发症的儿科患者的治疗模式和结局。

研究设计

病例系列,结合病历回顾。

设置

三级儿童保健医院。

受试者和方法

对 2008 年至 2018 年期间在一家机构就诊的 168 例患有伴有眶周并发症的复杂鼻窦炎的儿科患者进行了评估。记录并分析了人口统计学特征、疾病特征、住院期间的管理和结局。

结果

最常见的并发症是眶周蜂窝织炎,见于 49%的患儿。49%的患者接受了手术干预,其中 36%接受了先药物治疗后手术(MTS)。Chandler I 型患者有 30%接受了手术干预,Chandler II 型患者有 29%,Chandler III 型患者有 83%。19%的初始非手术患者在开始使用氨苄西林-舒巴坦后需要 MTS,而在开始使用其他抗生素方案的患者中,这一比例为 57%(<.01)。在开始使用氨苄西林-舒巴坦的初始非手术 Chandler I 至 II 型患者中,有 40%需要 MTS,而在开始使用其他抗生素方案的患者中,有 12%需要 MTS。手术患者的住院费用为 45056 美元,而非手术患者为 14311 美元(<.01)。手术加药物治疗(SMT)患者的住院费用为 45563 美元,而 MTS 患者的住院费用为 44393 美元(=.92)。

结论

早期非手术患者开始使用氨苄西林-舒巴坦后,MTS 的风险较低。MTS 的费用并不明显高于 SMT,且没有观察到显著的结局差异。

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