Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.
Department of Chemistry, University of Virginia, McCormick Rd, Charlottesville, Virginia 22904, United States.
J Org Chem. 2020 Jun 5;85(11):7342-7348. doi: 10.1021/acs.joc.0c00725. Epub 2020 May 27.
A novel BINOL-based near-IR fluorescent probe was designed and synthesized by incorporating a rhodamine-like dye. In the presence of Zn(II), this compound was found to exhibit highly enantioselective fluorescence enhancement at λ > 730 nm and λ = 690 nm when treated with 14 common amino acids in aqueous solution. An enantioselective fluorescence enhancement ratio up to 163 was observed. The mechanism of the fluorescence response of this probe was investigated by various spectroscopic methods.
设计并合成了一种新型基于 BINOL 的近红外荧光探针，该探针通过引入罗丹明类似染料。在 Zn(II)存在的条件下，该化合物在水溶液中与 14 种常见氨基酸作用时，在 λ > 730nm 和 λ = 690nm 处表现出高度的对映选择性荧光增强，观察到的荧光增强比高达 163。通过各种光谱方法研究了该探针荧光响应的机制。
