Stuedemann J A, Ciordia H, Walstrom D J, McCampbell H C
USDA, Southern Piedmont Conservation Research Center, Watkinsville, GA 30677.
Am J Vet Res. 1988 Dec;49(12):2090-3.
A 168-day study was conducted to evaluate the efficacy of morantel tartrate sustained-release bolus (MSRB) in controlling gastrointestinal parasitism in weaned calves during autumn-winter grazing in the temperature climate of southern United States. Sixty-two weanling Angus heifers were used to assess treatment differences. Six sentinel heifers were necropsied to assess pretrial gastrointestinal worm counts. The remaining 56 heifers were assigned to 4 groups of 14 heifers each and were placed on four 4.86-hectare dormant Bermuda grass pastures (1 group/pasture) that had been no-till interseeded with cereal rye in early October. Heifers in 2 groups were given 1 MSRB in early November; the other 2 groups served as nonmedicated controls. Three heifers (principals) from each of the 4 groups were necropsied on posttreatment days 57, 112, and 168 (end of study) for total worm recovery. Eight 5-month-old tracer steers, raised worm-free from birth, grazed the 4 pastures (2/pastures) for the first 21 days of the study and then were kept in drylot for 21 days before being necropsied. Level of larval contamination of pastures grazed by control and MSRB-treated heifers were comparable, because the mean number of nematodes recovered from tracer steers grazing the control and MSRB pastures were 47,449 and 53,835, respectively. At 28 days after treatment, MSRB-treated heifers had lower (P less than 0.05) mean egg counts/g of feces than did control heifers (280 vs 13).(ABSTRACT TRUNCATED AT 250 WORDS)
进行了一项为期168天的研究,以评估在美国南部温和气候下秋冬放牧期间,莫仑太尔酒石酸缓释大丸剂(MSRB)对断奶犊牛胃肠道寄生虫的控制效果。使用62头断奶的安格斯小母牛来评估治疗差异。对6头哨兵小母牛进行尸检以评估治疗前的胃肠道蠕虫数量。其余56头小母牛被分为4组,每组14头,并被放置在四个4.86公顷的休眠百慕大草场上(每组一个草场),这些草场在10月初进行了免耕并间播了黑麦。两组小母牛在11月初给予1剂MSRB;另外两组作为未用药的对照。在治疗后第57、112和168天(研究结束时),对4组中的每组3头小母牛(主要动物)进行尸检以进行全蠕虫回收。8头5个月大的示踪阉牛从出生起就无蠕虫饲养,在研究的前21天在这4个草场上放牧(每个草场2头),然后在进行尸检前在干栏中饲养21天。对照和MSRB处理的小母牛放牧的草场幼虫污染水平相当,因为从对照和MSRB草场放牧的示踪阉牛中回收的线虫平均数量分别为47,449和53,835。治疗后28天,MSRB处理的小母牛每克粪便中的平均虫卵数低于对照小母牛(P小于0.05)(280对13)。(摘要截断于250字)