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实时吲哚菁绿荧光原位还原在小儿活体肝移植中腹腔镜左外侧单段切除术的应用。

Laparoscopic Left Lateral Monosegmentectomy in Pediatric Living Donor Liver Transplantation Using Real-Time ICG Fluorescence In Situ Reduction.

机构信息

Department of Liver Transplantation, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

出版信息

J Gastrointest Surg. 2020 Sep;24(9):2185-2186. doi: 10.1007/s11605-020-04534-5. Epub 2020 May 12.

Abstract

BACKGROUND

Nowadays, laparoscopic left lateral sectionectomy has been acknowledged as a standard practice in pediatric living donor liver transplantation (PLDLT). We here report the first case of laparoscopic left lateral monosegmentectomy (L-LLM) in PLDLT using real-time ICG fluorescence in situ reduction in China.

METHOD

A 35-year-old father volunteered for living donation to his daughter who diagnosed with liver cirrhosis and portal hypertension after Kasai operation due to biliary atresia. Preoperative liver function was normal. Liver dynamic CT showed a left lateral graft volume of 387.5cm with a graft to recipient weight ratio (GRWR) of 4.45%. Ratio of the maximum thickness of the left lateral segment to the anteroposterior diameter of the recipient's abdominal cavity was 1.09. The estimated segment II volume was 245.3cm and GRWR was 2.82%. L-LLM was scheduled. No anatomic variation was seen.

RESULTS

The transection was divided into two stages. Stage I: Separating the left lateral section along the right side of sickle ligament. Stage II: Anatomic in situ reduction of segment III by using real-time ICG fluorescence. The left bile duct was transected above the bifurcation by ICG fluorescence cholangiography. The total operation time was 200 min without transfusion. The final graft weight was 225.2 g with GRWR of 2.59%. The donor was discharged uneventfully on postoperative day 4, while the graft function recovered to normal in recipient without any graft-related complication.

CONCLUSION

L-LLM with in situ reduction is feasible in PLDLT by using real-time ICG fluorescence in experienced transplant center.

摘要

背景

如今,腹腔镜左外叶切除术已被公认为小儿活体肝移植(PLDLT)中的标准术式。我们在此报告首例在中国使用实时吲哚菁绿荧光原位还原法行腹腔镜左外叶单节段切除术(L-LLM)的 PLDLT 病例。

方法

一位 35 岁的父亲自愿为其因胆道闭锁行Kasai 手术后出现肝硬化和门静脉高压的女儿捐献肝脏。术前肝功能正常。肝脏动态 CT 显示供肝左外侧叶体积为 387.5cm,供肝受体体重比(GRWR)为 4.45%。左外侧段最大厚度与受体腹腔前后径的比值为 1.09。预计段 II 体积为 245.3cm,GRWR 为 2.82%。计划行 L-LLM。未见解剖变异。

结果

肝离断分为两个阶段。第一阶段:沿镰状韧带右侧分离左外侧段。第二阶段:使用实时吲哚菁绿荧光行解剖原位还原段 III。ICG 荧光胆管造影在分叉上方横断左胆管。总手术时间为 200 分钟,无输血。最终供肝重量为 225.2g,GRWR 为 2.59%。供者术后第 4 天顺利出院,而受者的移植物功能恢复正常,无任何与移植物相关的并发症。

结论

在有经验的移植中心,使用实时吲哚菁绿荧光行 L-LLM 并原位还原是可行的。

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