Zhou Yikun, Han Xuan, Ren Fenggang, Li Qingshan, Chen Xue, Chu Dake, Wu Rongqian, Lyu Yi
National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061.
Regenerative Medicine and Surgical Engineering Research Center of Shaanxi Province, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061.
Zhongguo Yi Liao Qi Xie Za Zhi. 2020 Feb 8;44(2):172-178. doi: 10.3969/j.issn.1671-7104.2020.02.016.
Irreversible electroporation (IRE) is an emerging tissue ablation technique. Compared with thermal ablation technique such as radiofrequency, IRE can achieve focal ablation in a shorter time without heat sink effect while sparing the tissue scaffold. IRE has been demonstrated to be a feasible therapeutic modality for the liver, pancreatic, and prostatic cancer. In recent years, several studies regarding of catheter-directed IRE for digestive tract, bronchus, urinary tract, and myocardium have been performed, which preliminarily demonstrated the safety and efficacy of IRE for tissue ablation under endoscopic or interventional technique. This study summarized the research progress of catheter-directed IRE for tissue ablation. The critical technique and future direction of catheter-based IRE are prosp.
不可逆电穿孔（IRE）是一种新兴的组织消融技术。与射频等热消融技术相比，IRE能够在更短时间内实现局部消融，不存在热沉效应，同时保留组织支架。IRE已被证明是治疗肝癌、胰腺癌和前列腺癌的一种可行治疗方式。近年来，已经开展了多项关于导管引导下IRE用于消化道、支气管、泌尿道和心肌的研究，这些研究初步证明了IRE在内镜或介入技术下进行组织消融的安全性和有效性。本研究总结了导管引导下IRE用于组织消融的研究进展。基于导管的IRE的关键技术和未来方向令人期待。
