Salem G, Schlick W, Keiler A, Glöckler M, Möschl P, Radaszkiewicz T, Szalay S
Thoraxchir Vask Chir. 1977 Apr;25(2):61-7. doi: 10.1055/s-0028-1096683.
Pulmonary emphysema was induced in 8 bastard dogs by intratracheal instillation of Papain. Development of emphysema was documented by pulmonary function tests. The emphysematous animals underwent single lung homotransplantation. Postoperative bronchospirometric measurements revealed that up to the 6th week after transplantation there is no evidence of serious ventilation perfusion inbalance.
通过气管内注入木瓜蛋白酶,在8只杂种犬中诱发肺气肿。通过肺功能测试记录肺气肿的发展情况。对患有肺气肿的动物进行单肺同种移植。术后支气管肺量计测量结果显示,移植后直至第6周,均未发现严重通气灌注失衡的迹象。