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癌症遗传学。

Cancer Genetics.

机构信息

Department of Surgery, St. Vincent's Medical Center, Bridgeport, CT, USA; Frank H. Netter MD School of Medicine, Quinnipiac University, North Haven, CT, USA.

出版信息

Surg Clin North Am. 2020 Jun;100(3):483-498. doi: 10.1016/j.suc.2020.02.012. Epub 2020 Apr 16.

Abstract

For most individuals, cancer development is multifactorial; however, up to 10% of all cancers are related to an inherited genetic mutation. As health care shifts to having a greater emphasis on prevention, care providers, including general surgeons, will need to play a role in identifying patients at high risk for cancer development. Genetic testing provides a tool to determine those patients with a genetic mutation and to whom appropriate preventive care and treatment may be offered. It is imperative for general surgeons to understand the role genetics plays in the care of individual patients and their relatives.

摘要

对于大多数人来说,癌症的发生是多因素的;然而,高达 10%的癌症与遗传基因突变有关。随着医疗保健向预防为主的方向转变,包括普通外科医生在内的医护人员将需要在识别癌症高发风险患者方面发挥作用。基因检测提供了一种工具,可以确定那些有基因突变的患者,并为他们提供适当的预防和治疗。普通外科医生必须了解基因在个体患者及其亲属护理中的作用。

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