Godinho A F, Cavalcante G J, Machado M G, Faria T F, Gil T C, Coutinho R B, Garcia C
Departamento de Ciências Fisiológicas, Instituto de Biologia, Universidade Estadual do Rio de Janeiro, Brasil.
Braz J Med Biol Res. 1988;21(4):851-3.
A single dose of calcitonin (150 mIU/100 g body weight, sc) produced a significant decrease in liver antipyrine hydroxylase and aminopyrine demethylase activities. By contrast, pentobarbital sleeping time was not altered by calcitonin treatment. The present results indicate that acute calcitonin administration depresses the metabolism of substrates of the mixed function oxidase system of rat liver.
单次注射降钙素（150 mIU/100 g体重，皮下注射）可使肝脏安替比林羟化酶和氨基比林脱甲基酶活性显著降低。相比之下，降钙素治疗并未改变戊巴比妥睡眠时间。目前的结果表明，急性给予降钙素会抑制大鼠肝脏混合功能氧化酶系统底物的代谢。
