From the Park Nicollet Contact Dermatitis Clinic.
Dermatitis. 2021;32(1):32-37. doi: 10.1097/DER.0000000000000606.
Prescription and over-the-counter topical anesthetics are commonly used. Although allergy to amide and ester anesthetics is known, little has been reported on the nonamide, nonester pramoxine (pramocaine). This article briefly reviews allergy to topical anesthetics, provides detailed information on pramoxine, and describes characteristics of multiple patients with positive, relevant reactions to pramoxine.
处方和非处方局部麻醉剂是常用的。虽然酰胺和酯类局部麻醉剂过敏是已知的，但对于非酰胺、非酯普鲁卡因（普拉莫辛）的报道很少。本文简要回顾了局部麻醉剂过敏，详细介绍了普鲁卡因的信息，并描述了多个对普鲁卡因呈阳性相关反应的患者的特点。
