Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
The Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Spinal Cord Ser Cases. 2020 May 13;6(1):40. doi: 10.1038/s41394-020-0290-9.
Vertebral osteomyelitis (VO), spondylodiscitis, and spinal epidural abscesses (SEA) are infectious and inflammatory processes impacting the spine that cause major morbidity and mortality. They require prolonged hospital stays with expensive treatment regimens. Along with acute management, studies have provided evidence highlighting poor long-term outcomes. VO accounts for ~2% of all osteomyelitis. Recent data have illustrated an increase in incidence to 5.4 per 100,000 person years. The majority of patients that present with SEA and VO typically have some combination of back pain, fevers, and neurological deficits.
A 55-year-old woman with known history of hypertension and hyperlipidemia, status-post endoscopic repair of a Zenker's Diverticulum 3 weeks prior, presented to our outpatient clinic with a 2-week history of axial cervical spine pain as well as left sided scapular and deltoid pain. Further questioning and exam revealed no neurologic deficits or fever. As pain persisted and she did not respond to treatment, further imaging was performed. She was found to have cervical discitis, osteomyelitis, and a cervical epidural abscess.
Patients presenting with VO/SEA typically have spine pain with some other associated symptoms of spinal cord compression or fevers, making this a rare presentation. The urgency for discovery because of the need for emergent operative intervention is evident by the documented complications associated with a delay in diagnosis. This case report emphasizes the importance of always keeping VO/SEA on the differential for cervical spine pain even with lack of associated symptoms, in order to optimize patient care.
脊椎骨髓炎(VO)、脊椎椎间盘炎和脊椎硬膜外脓肿(SEA)是影响脊柱的感染性和炎症性疾病,会导致严重的发病率和死亡率。它们需要长时间住院治疗,并采用昂贵的治疗方案。除了急性治疗外,研究还提供了证据,强调了长期预后不佳。VO 占所有骨髓炎的约 2%。最近的数据表明,发病率增加到每 10 万人年 5.4 例。大多数出现 SEA 和 VO 的患者通常有背部疼痛、发热和神经功能缺损的组合症状。
一名 55 岁女性,有高血压和高血脂病史,3 周前因 Zenker 憩室经内镜修复后,因 2 周的颈痛和左侧肩胛带和三角肌疼痛到我们的门诊就诊。进一步询问和检查发现无神经功能缺损或发热。由于疼痛持续存在且她对治疗无反应,进一步进行了影像学检查。发现她患有颈椎椎间盘炎、骨髓炎和颈椎硬膜外脓肿。
患有 VO/SEA 的患者通常有脊椎疼痛,还有一些与脊髓压迫或发热相关的其他症状,这是一种罕见的表现。由于诊断延误相关并发症的存在,迫切需要发现并进行紧急手术干预,这一点很明显。这个病例报告强调了即使没有相关症状,也应始终将 VO/SEA 纳入颈椎疼痛的鉴别诊断中,以便优化患者的治疗效果。