Hibino Yukiko, Imai Ryosuke, Jinta Torahiko
Department of Internal Medicine St. Luke's International Hospital Tokyo Japan.
Department of Pulmonary Medicine St. Luke's International Hospital, Thoracic Center Tokyo Japan.
Respirol Case Rep. 2020 May 11;8(5):e00584. doi: 10.1002/rcr2.584. eCollection 2020 Jul.
Diffuse large B-cell lymphoma (DLBCL) with cavitary lung disease is rare and is often difficult to differentiate from primary lung cancer, granulomatous disease, or an infectious disease based on imaging findings alone. We herein report a case in which a patient with DLBCL presented with cavitary lung disease and splenic mass, which was diagnosed by transbronchial biopsy. DLBCL should be considered as a differential diagnosis in patients with cavitary lung diseases who have rare metastatic lesions for primary lung cancer, such as intra-abdominal lymph nodes or spleen.
伴有空洞性肺部疾病的弥漫性大B细胞淋巴瘤（DLBCL）较为罕见，仅根据影像学表现往往难以与原发性肺癌、肉芽肿性疾病或感染性疾病相鉴别。我们在此报告一例DLBCL患者，其表现为空洞性肺部疾病和脾脏肿块，经支气管活检得以确诊。对于伴有空洞性肺部疾病且有罕见的原发性肺癌转移病灶（如腹腔淋巴结或脾脏）的患者，应将DLBCL视为鉴别诊断之一。
