新型冠状病毒肺炎的药物治疗研究进展。
Research Progress of Drug Treatment in Novel Coronavirus Pneumonia.
机构信息
Molecular Biology Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, People's Republic of China.
Department of Pharmacy, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, People's Republic of China.
出版信息
AAPS PharmSciTech. 2020 May 13;21(4):130. doi: 10.1208/s12249-020-01679-z.
As of March 10, 2020, more than 100,000 novel coronavirus pneumonia cases have been confirmed globally. With the continuous spread of the new coronavirus pneumonia epidemic in even the world, prevention and treatment of the disease have become urgent tasks. The drugs currently being developed are not adequate to deal with this critical situation. In addition to being controlled through effective isolation, we need a rapid response from the healthcare and biotechnology industries to accelerate drug treatment research. By reviewing the currently available literature published at home and abroad, we summarize the current research progress of drug treatment during the epidemic period. At present, the drugs that can be used for treatment mainly include antiviral drugs, antimalarials, glucocorticoids, plasma therapy, biological agents, and traditional Chinese medicine. The effectiveness and safety of drug therapy need to be confirmed by more clinical studies.
截至 2020 年 3 月 10 日，全球已确诊超过 10 万例新型冠状病毒肺炎病例。随着新的冠状病毒肺炎疫情在全球范围内的不断蔓延，疾病的预防和治疗已成为当务之急。目前正在开发的药物还不足以应对这种危急情况。除了通过有效隔离进行控制外，我们还需要医疗保健和生物技术行业迅速做出反应，以加速药物治疗研究。通过回顾国内外现有的文献，我们总结了疫情期间药物治疗的研究进展。目前，可用于治疗的药物主要包括抗病毒药物、抗疟药、糖皮质激素、血浆疗法、生物制剂和中药。药物治疗的有效性和安全性需要更多的临床研究来证实。
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