一种新型血管5-羟色胺受体选择性拮抗剂可降低自发性高血压大鼠的血压。 - Suppr

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超能文献

A new selective antagonist of vascular serotonin receptors lowers blood pressure in spontaneously hypertensive rats.

作者信息

Salvati P, Vaghi F, Colombo M, Bianchi G

机构信息

Farmitalia Carlo Erba, Istituto Ricerche, Nerviano, Italy.

出版信息

Drugs. 1988;36 Suppl 1:105-9. doi: 10.2165/00003495-198800361-00019.

DOI:10.2165/00003495-198800361-00019

PMID:3240722

Abstract

摘要

相似文献

A new selective antagonist of vascular serotonin receptors lowers blood pressure in spontaneously hypertensive rats.一种新型血管5-羟色胺受体选择性拮抗剂可降低自发性高血压大鼠的血压。

Drugs. 1988;36 Suppl 1:105-9. doi: 10.2165/00003495-198800361-00019.

An investigation of the effects of intravenous injection of the 5-hydroxytryptamine 2 receptor antagonists ketanserin and LY 53857 on blood pressure in anesthetized spontaneously hypertensive rats.静脉注射5-羟色胺2受体拮抗剂酮色林和LY 53857对麻醉的自发性高血压大鼠血压影响的研究。

J Pharmacol Exp Ther. 1989 Feb;248(2):736-40.

Effects of antagonists of 5-hydroxytryptamine on blood pressure in the anesthetised spontaneously hypertensive rat.5-羟色胺拮抗剂对麻醉的自发性高血压大鼠血压的影响。

J Cardiovasc Pharmacol. 1987;10 Suppl 3:S59-61.

LY53857, a selective and potent serotonergic (5-HT2) receptor antagonist, does not lower blood pressure in the spontaneously hypertensive rat.LY53857，一种选择性强效血清素能（5-HT2）受体拮抗剂，不会降低自发性高血压大鼠的血压。

J Pharmacol Exp Ther. 1983 Nov;227(2):327-32.

5-HT2-receptor antagonists: alpha 1- vs. 5-HT2-receptor blocking properties in blood vessels.5-羟色胺2受体拮抗剂：血管中α1与5-羟色胺2受体阻断特性

J Cardiovasc Pharmacol. 1988;11 Suppl 1:S25-9.

Reduction in blood pressure in normal and spontaneously hypertensive rats by lergotrile mesylate.

J Pharm Pharmacol. 1979 Dec;31(12):814-7. doi: 10.1111/j.2042-7158.1979.tb13671.x.

Comparison between ketanserin and LY 53857 on vascular and cardiac 5-HT2 and alpha 1-adrenergic receptors in the pithed rat.酮色林与LY 53857对脊髓麻醉大鼠血管及心脏5-羟色胺2型和α1-肾上腺素能受体作用的比较

Arch Int Pharmacodyn Ther. 1990 Jul-Aug;306:57-64.

Effect of chronic ETA-selective endothelin receptor antagonism on blood pressure in experimental and genetic hypertension in rats.慢性ETA选择性内皮素受体拮抗剂对大鼠实验性高血压和遗传性高血压血压的影响。

Br J Pharmacol. 1997 Jul;121(5):935-40. doi: 10.1038/sj.bjp.0701224.

Hypotensive effects of eugenosedin-A with serotonin, alpha- and beta-adrenoceptor antagonistic activities in spontaneously hypertensive and normotensive rats.优格辛-A在自发性高血压大鼠和正常血压大鼠中具有5-羟色胺、α和β肾上腺素能受体拮抗活性的降压作用。

Pharmacology. 2004 Jun;71(2):91-101. doi: 10.1159/000076945.

Preclinical pharmacology of a new serotonergic receptor antagonist, LY281067.新型5-羟色胺能受体拮抗剂LY281067的临床前药理学

J Pharmacol Exp Ther. 1988 Jan;244(1):106-12.

本文引用的文献

Some quantitative uses of drug antagonists.药物拮抗剂的一些定量应用。

Br J Pharmacol Chemother. 1959 Mar;14(1):48-58. doi: 10.1111/j.1476-5381.1959.tb00928.x.

The antihypertensive effects of ketanserin (R 41468), a novel 5-hydroxytryptamine-blocking agent, in patients with essential hypertension.新型5-羟色胺阻断剂酮色林（R 41468）对原发性高血压患者的降压作用。

Clin Sci (Lond). 1981 Dec;61 Suppl 7:473s-476s. doi: 10.1042/cs061473s.

Mechanism of the hypotensive effect of ketanserin.酮色林降压作用的机制。

J Cardiovasc Pharmacol. 1982 Sep-Oct;4(5):829-38. doi: 10.1097/00005344-198209000-00020.

Vascular effects of ketanserin (R 41 468), a novel antagonist of 5-HT2 serotonergic receptors.酮色林（R 41 468）的血管效应，一种新型5-羟色胺2（5-HT2）血清素能受体拮抗剂。

J Pharmacol Exp Ther. 1981 Jul;218(1):217-30.

Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. II. Competitive antagonists.药物-受体解离常数的药理学评估。统计学评价。II. 竞争性拮抗剂。

J Pharmacol Exp Ther. 1971 Apr;177(1):13-24.

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