Duke-NUS Medical School, Singapore, Singapore.
Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore, Singapore.
Cardiovasc Intervent Radiol. 2020 Jul;43(7):963-970. doi: 10.1007/s00270-020-02497-3. Epub 2020 May 14.
The exact significance of type 2 endoleaks (T2ELs) and the indication and efficacy of treatment are widely debated. We report our experience with managing T2ELs in a tertiary Asian centre.
This was a retrospective study of patients who underwent endovascular abdominal aortic aneurysm repair (EVAR) between February 2006 and December 2016. Patients with T2ELs were identified, and their data were analysed.
A total of 156 patients underwent EVAR, of which 67 (42.9%) developed T2ELs. Seven were lost to follow-up. The remaining 60 patients had a mean follow-up period of 50.3 ± 33.9 months-34 (56.7%) experienced T2ELs early and the rest (43.3%) had late T2ELs. Forty-one patients had isolated T2EL, whilst 19 had concomitant T1EL and/or T3EL. Spontaneous resolution occurred in 25 patients (41.7%). All T2ELs with stable sac size were on continued surveillance. Amongst those with persistent T2ELs associated with sac growth (n = 17), 14 underwent intervention, of which 7 (50%) received > 1 embolisation procedure. A total of 16 transarterial embolisation and 8 translumbar embolisation procedures were performed. Technical success rate was 75%. In the intervention group, 5 (35.7%) had complete and sustained resolution, 7 had persistent/recurrent T2ELs but stable sac size, and 2 had progressive sac expansion. Overall mortality due to sac rupture occurred in 2 patients with concomitant T2EL and T1EL/T3EL.
T2ELs are common, albeit mostly benign if occurring in isolation and not in association with sac growth. Achieving complete T2EL resolution with embolisation is difficult even with reinterventions.
Level 2B, retrospective study.
2 型内漏(T2EL)的确切意义以及治疗的适应证和疗效仍存在广泛争议。我们报告了在亚洲一家三级中心处理 T2EL 的经验。
这是一项回顾性研究,纳入了 2006 年 2 月至 2016 年 12 月期间接受腹主动脉瘤腔内修复术(EVAR)的患者。对 T2EL 患者进行了识别,并对其数据进行了分析。
共 156 例患者接受了 EVAR,其中 67 例(42.9%)发生了 T2EL。7 例患者失访。其余 60 例患者的平均随访时间为 50.3±33.9 个月-34 例(56.7%)早期发生 T2EL,其余(43.3%)发生晚期 T2EL。41 例患者仅存在 T2EL,而 19 例患者同时存在 T1EL 和/或 T3EL。25 例(41.7%)患者的 T2EL 自发缓解。所有 T2EL 且瘤囊大小稳定者继续接受监测。在持续存在 T2EL 并伴有瘤囊增大的患者中(n=17),14 例接受了干预,其中 17 例行介入治疗,7 例(50%)接受了>1 次的栓塞治疗。共进行了 16 次经动脉栓塞术和 8 次经皮穿刺腰椎穿刺栓塞术。技术成功率为 75%。在干预组中,5 例(35.7%)完全且持续缓解,7 例瘤囊大小稳定但仍存在/复发 T2EL,2 例瘤囊持续增大。2 例患者同时存在 T2EL 和 T1EL/T3EL,因瘤囊破裂导致总体死亡率。
如果 T2EL 孤立存在且不伴瘤囊增大,则通常为良性,尽管较为常见。即使进行多次介入治疗,也很难使 T2EL 完全缓解。
2B 级,回顾性研究。