BACKGROUND: Artificial intelligence (AI) is the way to model human intelligence to accomplish certain tasks without much intervention of human beings. The term AI was first used in 1956 with The Logic Theorist program, which was designed to simulate problem-solving ability of human beings. There have been a significant amount of research works using AI in order to determine the advantages and disadvantages of its applicabication and, future perspectives that impact different areas of society. Even the remarkable impact of AI can be transferred to the field of healthcare with its use in pharmaceutical and biomedical studies crucial for the socioeconomic development of the population in general within different studies, we can highlight those that have been conducted with the objective of treating diseases, such as cancer, neurodegenerative diseases, among others. In parallel, the long process of drug development also requires the application of AI to accelerate research in medical care. METHODS: This review is based on research material obtained from PubMed up to Jan 2020. The search terms include "artificial intelligence", "machine learning" in the context of research on pharmaceutical and biomedical applications. RESULTS: This study aimed to highlight the importance of AI in the biomedical research and also recent studies that support the use of AI to generate tools using patient data to improve outcomes. Other studies have demonstrated the use of AI to create prediction models to determine response to cancer treatment. CONCLUSION: The application of AI in the field of pharmaceutical and biomedical studies has been extensive, including cancer research, for diagnosis as well as prognosis of the disease state. It has become a tool for researchers in the management of complex data, ranging from obtaining complementary results to conventional statistical analyses. AI increases the precision in the estimation of treatment effect in cancer patients and determines prediction outcomes.