Ceruso M, Lauri G, Bufalini C, Bartolozzi G, Bernardini S, Cinti S, Morroni M, Matucci-Cerinic M
U.O. Chirurgia della Mano e Microchirurgia Ricostruttiva, Centro Traumatologico Ortopedico, Firenze, Italy.
J Hand Surg Am. 1988 Sep;13(5):765-70. doi: 10.1016/s0363-5023(88)80145-x.
Diabetic hand syndrome is a condition affecting about 30% of patients with insulin-requiring juvenile diabetes. Characteristic findings in this syndrome are mild- to- moderately severe joint contractures of the fingers, particularly at the proximal interphalangeal joints in the ring and small fingers, and thickening of the skin of the dorsum of the hand. There is no evidence of palmar fascial thickening or Dupuytren's contracture. Occasionally other joints may be involved, such as the wrists, elbows, hips, knees, and toes. In the case presented in this report light and electron microscopic studies showed that the disease presents aspects similar to those of other "fibrotic diseases" as described by Kisher and Speer. Surgical treatment was only partially beneficial in this patient.
糖尿病手综合征是一种影响约30%需要胰岛素治疗的青少年糖尿病患者的病症。该综合征的特征性表现为手指轻度至中度严重的关节挛缩,尤其是环指和小指的近端指间关节,以及手背皮肤增厚。没有掌腱膜增厚或杜普伊特伦挛缩的证据。偶尔其他关节也可能受累,如手腕、肘部、髋部、膝盖和脚趾。在本报告所呈现的病例中,光镜和电镜研究表明,该疾病呈现出与Kisher和Speer所描述的其他“纤维化疾病”相似的特征。手术治疗对该患者仅部分有效。