Wang Lei, Xie Mengfan, Hong Liwen, Zhang Chen, Zhang Tianyu, Fan Rong, Zhong Jie, Wang Zhengting
Department of Gastroenterology, Ruijin Hospital, Shanghai, Jiaotong University School of Medicine, Shanghai, China.
Gastroenterol Res Pract. 2020 Apr 27;2020:8121625. doi: 10.1155/2020/8121625. eCollection 2020.
Double-balloon enteroscopy (DBE) is widely used worldwide. However, comparisons between the diagnostic yields in adults and the elderly remain scarce.
The aim of this study is to compare the diagnostic yields and safety of DBE between adults and elderly with obscure gastrointestinal bleeding and incomplete small bowel obstruction.
We retrospectively reviewed patients who underwent DBE with indication of obscure gastrointestinal bleeding or incomplete small bowel obstruction in Ruijin Hospital and classified them into adults (18-64 years old) and elderly (≥65 years old). Clinical characteristics, diagnostic yields, and postoperative complications were collected and further analyzed.
A total of 877 DBE procedures, 729 in adults and 148 in the elderly, were performed. In the patients with OGIB, the adults showed a higher frequency of Meckel's diverticulum compared with the elderly (4.6% vs. 0.9%, = 0.032). Angioectasia was higher in frequency in the elderly than in the adults (25.9% vs. 17.9%, = 0.048). In patients with incomplete small bowel obstruction, the elderly were more likely to have adenocarcinoma than the adults (19.4% vs. 7.1%, = 0.038). The adults had higher tendency to have Crohn's disease than the elderly (23.4% vs. 8.3%, = 0.045). Most of the postoperative complications were mild. The adults and elderly displayed comparable tolerance to DBE ( > 0.05).
DBE has a high diagnostic yield in small bowel disorders, and a slight difference in disease spectrum was observed between the adults and elderly. DBE can be well-tolerated in the elderly.
双气囊小肠镜检查(DBE)在全球范围内广泛应用。然而,关于成人与老年人诊断率的比较仍然很少。
本研究旨在比较成人和老年人在不明原因胃肠道出血和不完全性小肠梗阻患者中DBE的诊断率和安全性。
我们回顾性分析了在瑞金医院因不明原因胃肠道出血或不完全性小肠梗阻而接受DBE检查的患者,并将其分为成人组(18 - 64岁)和老年组(≥65岁)。收集临床特征、诊断率和术后并发症并进行进一步分析。
共进行了877例DBE检查,其中成人729例,老年人148例。在不明原因胃肠道出血患者中,成人组梅克尔憩室的发生率高于老年组(4.6%对0.9%,P = 0.032)。老年组血管扩张的发生率高于成人组(25.9%对17.9%,P = 0.048)。在不完全性小肠梗阻患者中,老年组腺癌的发生率高于成人组(19.4%对7.1%,P = 0.038)。成人组克罗恩病发生率高于老年组(23.4%对8.3%,P = 0.045)。大多数术后并发症为轻度。成人和老年人对DBE的耐受性相当(P>0.05)。
DBE对小肠疾病具有较高的诊断率,成人和老年人之间疾病谱存在轻微差异。老年人对DBE耐受性良好。