Beriwal Nitya, Misko Albert L, Duhaime Ann-Christine
Medicine, Lady Hardinge Medical College, New Delhi, IND.
Department of Neurology, Massachusetts General Hospital, and Harvard Medical School, Boston, USA.
Cureus. 2020 May 7;12(5):e8011. doi: 10.7759/cureus.8011.
Pediatric traumatic brain injury (TBI) is a major cause of concern worldwide. Non-accidental traumatic (NAT) brain injury is common in infants. Since infants may present with varied presentations post-NAT, a healthy suspicion is required for effective diagnosis. Infants with NAT and, rarely, accidental subdural hemorrhage may exhibit a clinicoradiologically dissociative presentation, with their behavior appearing to reflect better function than what becomes apparent with maturation. Injury to the developing brain can result in extensive damage consistent with the "big black brain" phenomenon, which predicts poor prognosis. Sequential magnetic resonance imaging (MRI) is important to understand insults to the developing brain for follow-up and prognostication. Pediatric traumatic brain injury (TBI) is a major cause of concern worldwide. NAT brain injury is common in infants, who may present with varied presentations post-NAT, hence, a healthy suspicion is required for effective diagnosis. Infants with NAT and, rarely, an accidental subdural hemorrhage may exhibit a clinicoradiologically dissociative presentation with their behavior appearing to reflect better function than what becomes apparent with maturation. Injury to the developing brain can result in extensive damage consistent with the "big black brain" phenomenon, which predicts poor prognosis. Sequential MRI is important to understand insults to the developing brain for follow-up and prognostication.
小儿创伤性脑损伤（TBI）是全球关注的主要原因。非意外性创伤性（NAT）脑损伤在婴儿中很常见。由于婴儿在NAT后可能表现出各种症状，因此有效诊断需要保持高度警惕。患有NAT的婴儿，以及罕见的意外性硬膜下出血的婴儿，可能会出现临床放射学分离表现，其行为似乎反映出比随着成熟而显现出的更好的功能。发育中的大脑受到损伤会导致与“大黑脑”现象一致的广泛损伤，这预示着预后不良。连续磁共振成像（MRI）对于了解发育中的大脑所受损伤以便进行随访和预后评估很重要。小儿创伤性脑损伤（TBI）是全球关注的主要原因。NAT脑损伤在婴儿中很常见，这些婴儿在NAT后可能表现出各种症状，因此有效诊断需要保持高度警惕。患有NAT的婴儿，以及罕见的意外性硬膜下出血的婴儿，可能会出现临床放射学分离表现，其行为似乎反映出比随着成熟而显现出的更好的功能。发育中的大脑受到损伤会导致与“大黑脑”现象一致的广泛损伤，这预示着预后不良。连续MRI对于了解发育中的大脑所受损伤以便进行随访和预后评估很重要。
