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创伤性脑损伤的神经影像学

Neuroimaging of traumatic brain injury.

作者信息

Le Tuong H, Gean Alisa D

机构信息

Department of Radiology, Brain and Spinal Cord Injury Center, San Francisco General Hospital, San Francisco, CA, USA.

出版信息

Mt Sinai J Med. 2009 Apr;76(2):145-62. doi: 10.1002/msj.20102.

Abstract

In this article, the neuroradiological evaluation of traumatic brain injury is reviewed. Different imaging strategies in the assessment of traumatic brain injury are initially discussed, and this is followed by a review of the imaging characteristics of both primary and secondary brain injuries. Computed tomography remains the modality of choice for the initial assessment of acute head injury because it is fast, widely available, and highly accurate in the detection of skull fractures and acute intracranial hemorrhage. Magnetic resonance imaging is recommended for patients with acute traumatic brain injury when the neurological findings are unexplained by computed tomography. Magnetic resonance imaging is also the modality of choice for the evaluation of subacute or chronic traumatic brain injury. Mild traumatic brain injury continues to be difficult to diagnose with current imaging technology. Advanced magnetic resonance techniques, such as diffusion-weighted imaging, magnetic resonance spectroscopy, and magnetization transfer imaging, can improve the identification of traumatic brain injury, especially in the case of mild traumatic brain injury. Further research is needed for other advanced imaging methods such as magnetic source imaging, single photon emission tomography, and positron emission tomography.

摘要

本文对创伤性脑损伤的神经放射学评估进行了综述。首先讨论了评估创伤性脑损伤时的不同成像策略,随后对原发性和继发性脑损伤的成像特征进行了综述。计算机断层扫描仍然是急性头部损伤初始评估的首选方式,因为它速度快、广泛可用,并且在检测颅骨骨折和急性颅内出血方面高度准确。对于急性创伤性脑损伤患者,若计算机断层扫描无法解释其神经学表现,则建议进行磁共振成像检查。磁共振成像也是评估亚急性或慢性创伤性脑损伤的首选方式。目前的成像技术仍然难以诊断轻度创伤性脑损伤。先进的磁共振技术,如扩散加权成像、磁共振波谱和磁化传递成像,可改善创伤性脑损伤的识别,尤其是在轻度创伤性脑损伤的情况下。对于其他先进成像方法,如磁源成像、单光子发射断层扫描和正电子发射断层扫描,还需要进一步研究。

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