Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Clinical Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.
Can J Cardiol. 2020 Jul;36(7):1161.e1-1161.e2. doi: 10.1016/j.cjca.2020.02.097. Epub 2020 Mar 5.
Most allergic reactions to radiocontrast media can be managed with a pretreatment protocol of steroids and antihistamines. However, in rare circumstances, patients can have severe allergic symptoms despite pretreatment. In this case, we highlight the use of a novel desensitization protocol in a patient with a severe breakthrough contrast allergy and unstable angina that allowed for successful percutaneous coronary intervention. The protocol was well tolerated, feasible, and might allow other patients with similar allergies to undergo angiography and imaging studies successfully that require the use of radiocontrast media.
大多数造影剂过敏反应可以通过皮质类固醇和抗组胺药物预处理方案来控制。然而，在极少数情况下，患者即使进行了预处理也可能出现严重的过敏症状。在这种情况下，我们重点介绍了一种新的脱敏方案在一名严重突破性对比过敏和不稳定型心绞痛患者中的应用，该方案成功地进行了经皮冠状动脉介入治疗。该方案耐受良好、可行，可能使其他有类似过敏的患者成功地进行需要使用造影剂的血管造影和影像学研究。
