• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

多耐药性腰骶脊柱结核导致广泛破坏并伴有腰骶脊柱后凸。

Multidrug-resistant tuberculosis of lumbosacral spine producing extensive destruction with lumbosacral kyphosis.

机构信息

Department of Orthopedics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.

Department of Orthopedics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India

出版信息

BMJ Case Rep. 2020 May 14;13(5):e234246. doi: 10.1136/bcr-2020-234246.

DOI:10.1136/bcr-2020-234246
PMID:32414775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7232617/
Abstract

It is uncommon to get lumbosacral junction deformity due to tuberculosis. Lumbosacral junction alignment is of paramount importance in maintaining global sagittal balance. In this case report, we present a case of a 42-year-old woman with multidrug-resistant tuberculosis of lumbosacral spine with complete destruction of L3, L4 and L5 vertebra with partial destruction of L2 and S1 vertebra leading to significant shortening and lumbosacral kyphosis. The patient had severe axial low back pain, inability to sleep in supine position due to deformity and difficulty in walking due to loss of spinal alignment. The patient was treated with 6 weeks of antituberculous drugs followed by all posterior decompression with instrumentation from D10 to S2 with a reconstruction of anterior vertebral bodies with the help of an expandable cage. Antituberculous treatment was continued for 18 months. At present, the patient is asymptomatic with no neurological deficit and has completed 3.5 years of regular follow-up.

摘要

由于结核病而导致腰骶关节畸形并不常见。腰骶关节对线对于维持整体矢状面平衡至关重要。在本病例报告中,我们介绍了一位 42 岁女性,患有腰骶脊柱多药耐药性结核,L3、L4 和 L5 椎体完全破坏,L2 和 S1 椎体部分破坏,导致明显缩短和腰骶角后凸。患者有严重的轴向腰痛,由于畸形而无法仰卧入睡,由于脊柱对线丢失而行走困难。患者接受了 6 周的抗结核药物治疗,随后进行了从 D10 到 S2 的所有后路减压和器械固定,在可扩张 cage 的帮助下重建了前椎体。抗结核治疗持续了 18 个月。目前,患者无症状,无神经功能缺损,已完成 3.5 年的定期随访。

相似文献

1
Multidrug-resistant tuberculosis of lumbosacral spine producing extensive destruction with lumbosacral kyphosis.多耐药性腰骶脊柱结核导致广泛破坏并伴有腰骶脊柱后凸。
BMJ Case Rep. 2020 May 14;13(5):e234246. doi: 10.1136/bcr-2020-234246.
2
Tuberculous lesions of the lumbosacral region. A 15-year follow-up of patients treated by ambulant chemotherapy.腰骶部结核病变。对接受门诊化疗患者的15年随访。
Spine (Phila Pa 1976). 1998 May 15;23(10):1163-7. doi: 10.1097/00007632-199805150-00018.
3
[Combined anterior and posterior surgeries for lumbarsacral junction tuberculosis].腰骶部结核的前后联合手术
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2008 Apr;22(4):408-10.
4
Global Reconstruction for Extensive Destruction in Tuberculosis of the Lumbar Spine and Lumbosacral Junction: A Case Report.广泛破坏的腰椎和腰骶连接处结核的全球重建:一例报告。
Global Spine J. 2015 Aug;5(4):e17-21. doi: 10.1055/s-0034-1395780. Epub 2014 Nov 10.
5
Tuberculous spondylitis of the lumbosacral region: long-term follow-up of patients treated by chemotherapy, transpedicular drainage, posterior instrumentation, and fusion.腰骶部结核性脊柱炎:化疗、经椎弓根引流、后路内固定及融合治疗患者的长期随访
J Spinal Disord Tech. 2005 Oct;18(5):425-9. doi: 10.1097/01.bsd.0000171627.11171.6f.
6
Conservative treatment of tuberculosis of the lumbar and lumbosacral spine.腰椎及腰骶椎结核的保守治疗
Clin Orthop Relat Res. 2002 May(398):40-9. doi: 10.1097/00003086-200205000-00007.
7
Posterior vertebral column resection in fixed lumbosacral deformity.固定性腰骶部畸形的后路脊柱切除术
Spine (Phila Pa 1976). 2005 Dec 1;30(23):E703-10. doi: 10.1097/01.brs.0000188190.90034.be.
8
Post-tubercular Lumbosacral Kyphotic Deformity in a 11-Year-Old Child: A Case Report.11 岁儿童结核后胸腰椎后凸畸形:病例报告。
JBJS Case Connect. 2024 May 31;14(2). doi: e24.00066. eCollection 2024 Apr 1.
9
Tuberculosis of the lumbosacral junction. Long-term follow-up of 26 cases.腰骶关节结核。26例长期随访
J Bone Joint Surg Br. 1990 Jul;72(4):675-8. doi: 10.1302/0301-620X.72B4.2143192.
10
Morphological changes during growth in healed childhood spinal tuberculosis: a 15-year prospective study of 61 children treated with ambulatory chemotherapy.儿童脊柱结核愈合过程中的生长形态学变化:对61例接受门诊化疗儿童的15年前瞻性研究
J Pediatr Orthop. 2006 Nov-Dec;26(6):716-24. doi: 10.1097/01.bpo.0000230326.21707.71.

引用本文的文献

1
Study on the Association Network of Tuberculosis Lesions in Adult Extrapulmonary Tuberculosis in China: A Large-Scale Multicenter Observational Study.中国成人肺外结核病变关联网络研究:一项大规模多中心观察性研究
Can J Infect Dis Med Microbiol. 2025 May 16;2025:4944872. doi: 10.1155/cjid/4944872. eCollection 2025.

本文引用的文献

1
Global Reconstruction for Extensive Destruction in Tuberculosis of the Lumbar Spine and Lumbosacral Junction: A Case Report.广泛破坏的腰椎和腰骶连接处结核的全球重建:一例报告。
Global Spine J. 2015 Aug;5(4):e17-21. doi: 10.1055/s-0034-1395780. Epub 2014 Nov 10.
2
The femoro-sacral posterior angle: an anatomical sagittal pelvic parameter usable with dome-shaped sacrum.股骨-骶骨后角:一个可用于穹窿形骶骨的解剖学矢状位骨盆参数。
Eur Spine J. 2007 Feb;16(2):219-25. doi: 10.1007/s00586-006-0090-3. Epub 2006 Mar 17.
3
Tuberculosis of the lumbosacral junction. Long-term follow-up of 26 cases.腰骶关节结核。26例长期随访
J Bone Joint Surg Br. 1990 Jul;72(4):675-8. doi: 10.1302/0301-620X.72B4.2143192.