Artiaco Stefano, Fusini Federico, Pennacchio Gioacchino, Colzani Giulia, Battiston Bruno, Bianchi Pasquale
Department of Orthopaedics and Traumatology, Hand Upper Limb Surgery Unit, Orthopaedic and Trauma Center, AOU Città della Salute e della Scienza di Torino, University of Turin, via Zuretti 29, 10126, Turin, Italy.
Department of Orthopaedic and Traumatology, Regina Montis Regalis Hospital, ASL CN1, Via S. Rocchetto99, 12084, Mondovì, Italy.
Eur J Orthop Surg Traumatol. 2020 Oct;30(7):1251-1255. doi: 10.1007/s00590-020-02697-0. Epub 2020 May 15.
Sarcopenia is a clinical syndrome characterized by the reduction in muscle mass, strength and physical ability. Although proximal femur fractures are one of the major burdens affecting the ageing population, distal radius fractures are equally important for frequency, clinical and social consequences. The aim of this study is to evaluate the incidence of sarcopenia in distal radius fractures and clinical implications in functional recovery.
Scopus and PubMed search was performed to find relationship between sarcopenia and distal radius fractures. Literature search was performed between 2009 and 2019 including clinical trials and clinical studies related to "sarcopenia and distal radius fracture" and "sarcopenia and wrist fracture". After identification, studies were screened and analysed through the Oxford Level of Evidence.
According to the inclusion and exclusion criteria, five articles were included. Four articles analysed the incidence of sarcopenia and its role as a risk factor in patients with distal radial fractures, while one article focused on sarcopenia and clinical results of surgical treatment of distal radius fractures. Incidence of sarcopenia in patients older than 50 years with distal radius fracture varied between 29.7% and 31.7%. Patients with distal radial fractures did not show a significant inferior muscle mass than control group in examined population. Functional results of surgery were significantly inferior in sarcopenic patients than control group (no sarcopenia).
About 30% of patients older than 50 years with distal radius fracture suffered by sarcopenia; sarcopenic patients surgically treated had worse clinical results than no sarcopenic patients. Further studies with larger samples are needed to confirm these preliminary results.
肌肉减少症是一种以肌肉质量、力量和身体能力下降为特征的临床综合征。虽然股骨近端骨折是影响老年人群的主要负担之一,但桡骨远端骨折在发生频率、临床及社会后果方面同样重要。本研究旨在评估桡骨远端骨折患者中肌肉减少症的发生率及其对功能恢复的临床影响。
通过Scopus和PubMed数据库进行检索,以寻找肌肉减少症与桡骨远端骨折之间的关系。检索时间范围为2009年至2019年,纳入与“肌肉减少症和桡骨远端骨折”以及“肌肉减少症和腕部骨折”相关的临床试验和临床研究。筛选出符合条件的研究后,依据牛津证据水平进行分析。
根据纳入和排除标准,共纳入5篇文章。4篇文章分析了肌肉减少症的发生率及其作为桡骨远端骨折患者危险因素的作用,1篇文章聚焦于肌肉减少症与桡骨远端骨折手术治疗的临床结果。50岁以上桡骨远端骨折患者中肌肉减少症的发生率在29.7%至31.7%之间。在研究人群中,桡骨远端骨折患者的肌肉质量与对照组相比无显著降低。肌肉减少症患者手术的功能结果显著差于对照组(无肌肉减少症患者)。
50岁以上桡骨远端骨折患者中约30%患有肌肉减少症;接受手术治疗的肌肉减少症患者临床结果比无肌肉减少症患者更差。需要进一步开展更大样本量的研究以证实这些初步结果。