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复发性肝细胞癌导致上消化道出血的罕见原因:一例报告

An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report.

作者信息

Liu Yuk Ho, Lo Eugene Yee Juen, Lee Kit Fai, Chong Charing Ching Ning, Lai Paul Bo San

机构信息

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Prince of Wales Hospital, Hong Kong.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Prince of Wales Hospital, Hong Kong.

出版信息

Int J Surg Case Rep. 2020;70:83-86. doi: 10.1016/j.ijscr.2020.04.008. Epub 2020 May 11.

DOI:10.1016/j.ijscr.2020.04.008
PMID:32416488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7226638/
Abstract

INTRODUCTION

Upper gastrointestinal bleeding (UGIB) in patients suffering from hepatocellular carcinoma (HCC) is usually due to oesophageal or gastric varices secondary to portal hypertension. Very rarely, HCC can directly invade into the stomach or duodenum resulting in UGIB.

PRESENTATION OF CASE

A 62-year-old man presented to the emergency department for haematemesis and tarry stool. He was a hepatitis B carrier and had received open radiofrequency ablation and wedge resection for HCC previously. Urgent endoscopy and contrast computed tomography confirmed recurrent HCC invading into the duodenum. The patient received radical resection and remained disease free for 7 years after the operation.

DISCUSSION

Direct invasion into gastrointestinal tract by HCC is rare. Different modalities of treatment have been reported in the literature with variable success. En-bloc resection should be considered if surgically feasible in order to achieve good haemostasis and possible long term survival.

CONCLUSION

Upper gastrointestinal bleeding is a rare presentation of hepatocellular carcinoma and long term survival can be achieved by curative surgery.

摘要

引言

肝细胞癌(HCC)患者的上消化道出血(UGIB)通常是由于门静脉高压继发的食管或胃静脉曲张所致。HCC直接侵犯胃或十二指肠导致UGIB的情况非常罕见。

病例介绍

一名62岁男性因呕血和柏油样便就诊于急诊科。他是乙肝携带者,此前曾接受过HCC的开放性射频消融和楔形切除术。紧急内镜检查和增强计算机断层扫描证实复发性HCC侵犯十二指肠。患者接受了根治性切除术,术后7年无疾病复发。

讨论

HCC直接侵犯胃肠道的情况罕见。文献报道了不同的治疗方式,效果各异。如果手术可行,应考虑整块切除,以实现良好的止血和可能的长期生存。

结论

上消化道出血是肝细胞癌的一种罕见表现,根治性手术可实现长期生存。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/ebae4dd25462/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/f764408eb4a6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/ffb391d69da5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/0c90c78533f2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/ebae4dd25462/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/f764408eb4a6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/ffb391d69da5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/0c90c78533f2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e151/7226638/ebae4dd25462/gr4.jpg

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本文引用的文献

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Management of hepatocellular carcinoma with portal vein tumor thrombosis: Review and update at 2016.门静脉癌栓型肝细胞癌的管理:2016年回顾与更新
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Rare cause of upper gastrointestinal bleeding owing to hepatic cancer invasion: a case report.
肝癌侵犯导致上消化道出血的罕见原因:一例报告
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Massive upper gastrointestinal hemorrhage due to invasive hepatocellular carcinoma and hepato-gastric fistula.因侵袭性肝细胞癌和肝胃瘘导致的上消化道大出血。
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