子宫内膜异位症相关卵巢上皮癌：双侧卵巢原发性同步不同细胞类型。
Endometriosis-associated epithelial ovarian cancer: Primary synchronous different cellular type on each ovary.
机构信息
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
Department of Pathology and Laboratory Medicine Taipei Veterans General Hospital, Taipei, Taiwan.
出版信息
Taiwan J Obstet Gynecol. 2020 May;59(3):460-463. doi: 10.1016/j.tjog.2020.03.024.
OBJECTIVE
Endometriosis-associated epithelial ovarian cancer (EOC) is a specific category of EOC, containing either endometrioid or clear cell carcinoma subtype. The characteristic of endometriosis-associated EOC includes an early stage at the diagnosis, presence of single histology type, and better prognosis. The synchronous two subtypes of endometriosis-associated EOC and presentation of far-advanced stage status at the initial diagnosis is rarely reported.
CASE REPORT
We reported a 60-year-old postmenopausal woman with FIGO IA endometriosis-associated endometrioid carcinoma at right ovary and FIGO IVA endometriosis-associated clear cell carcinoma at left ovary, right tube, omentum, lymph node and cytology of pleural effusion and ascites treated with optimal debulking surgery and dose-intensity taxane/platinum based chemotherapy.
CONCLUSION
This case report confirms the long-term concept that clear cell carcinoma has much more aggressive behavior than endometrioid cell carcinoma does, regardless of association of endometriosis or not.
目的
子宫内膜异位症相关的卵巢上皮癌（EOC）是 EOC 的一个特殊类型，包含子宫内膜样或透明细胞癌亚型。子宫内膜异位症相关的 EOC 的特征包括诊断时处于早期、存在单一组织学类型和较好的预后。同时存在子宫内膜异位症相关的两种亚型和初始诊断时表现为晚期状态的情况很少见。
病例报告
我们报告了一例 60 岁绝经后妇女，右侧卵巢为 FIGO IA 期子宫内膜异位症相关子宫内膜样癌，左侧卵巢、右侧输卵管、网膜、淋巴结和胸腔积液及腹水细胞学为 FIGO IVA 期子宫内膜异位症相关透明细胞癌，接受了最佳肿瘤细胞减灭术和剂量密集型紫杉醇/铂类化疗。
结论
本病例报告证实了长期以来的观点，即无论是否合并子宫内膜异位症，透明细胞癌的侵袭性行为都比子宫内膜样细胞癌更具侵袭性。
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