秋水仙碱与白细胞减少：临床意义。
Colchicine and Leukopenia: Clinical Implications.
机构信息
Division of Pediatric Rheumatology, Department of Pediatrics, Ankara, Turkey.
Division of Pediatric Hematology, Department of Pediatrics, Hacettepe University, Ankara, Turkey.
出版信息
J Pediatr. 2020 Sep;224:166-170.e1. doi: 10.1016/j.jpeds.2020.03.065. Epub 2020 May 13.
Colchicine is the mainstay of treatment for familial Mediterranean fever. We investigated the frequency of leukopenia in 213 patients with familial Mediterranean fever treated with standard doses of colchicine (0.5-2.0 mg/day). We found that 23 patients (10.8%) had reversible leukopenia, 3 moderate, and none severe and that their rate of infections was not increased.
秋水仙碱是家族性地中海热治疗的主要药物。我们研究了 213 名接受标准剂量秋水仙碱（0.5-2.0 毫克/天）治疗的家族性地中海热患者的白细胞减少症发生率。我们发现 23 名患者（10.8%）存在可逆性白细胞减少症，其中 3 例为中度，无严重白细胞减少症，且其感染率并未增加。
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