克罗恩病肠纤维化的横断面成像评估。

Cross-sectional imaging for assessing intestinal fibrosis in Crohn's disease.

机构信息

Department of Radiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China.

Department of Ultrasound, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China.

出版信息

J Dig Dis. 2020 Jun;21(6):342-350. doi: 10.1111/1751-2980.12881.

DOI:10.1111/1751-2980.12881

PMID:32418328

Abstract

More than 30% of patients with Crohn's disease (CD) develop fibrotic strictures in the bowel as the disease progresses. Excessive deposition of extracellular matrix components in the submucosa and smooth muscle hypertrophy or hyperplasia are the main features of fibrosis in CD. Cross-sectional imaging technology provides a wealth of information on the anatomy, histological composition, and physiological function of the bowel, allowing for a non-invasive and complete evaluation of associated abnormalities. This review summarizes recent advances in and the potential technologies of cross-sectional imaging for assessing intestinal fibrosis in CD, including ultrasound imaging, computed tomography, and magnetic resonance imaging.

摘要

超过 30%的克罗恩病（CD）患者随着疾病的进展会出现肠道纤维性狭窄。在 CD 中，黏膜下和平滑肌过度的细胞外基质成分沉积以及肥厚或增生是纤维化的主要特征。横断面成像技术为肠壁的解剖结构、组织学组成和生理功能提供了丰富的信息，可实现对相关异常的非侵入性和全面评估。本综述总结了用于评估 CD 肠纤维化的横断面成像的最新进展和潜在技术，包括超声成像、计算机断层扫描和磁共振成像。