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Vascularized gastroepiploic lymph node transfer significantly improves breast cancer-related lymphedema.血管化胃网膜淋巴结转移术显著改善乳腺癌相关淋巴水肿。
J Surg Oncol. 2020 Jan;121(1):163-167. doi: 10.1002/jso.25607. Epub 2019 Jul 16.
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Influence of vascularized lymph node transfer (VLNT) flap positioning on the response to breast cancer-related lymphedema treatment.带血管蒂淋巴结转移(VLNT)皮瓣定位对乳腺癌相关淋巴水肿治疗反应的影响。
Rev Col Bras Cir. 2019 May 27;46(2):e2156. doi: 10.1590/0100-6991e-20192156.
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Combined double vascularized lymph node transfers and modified radical reduction with preservation of perforators for advanced stages of lymphedema.联合双血管化淋巴结转移术及保留穿支的改良根治性减容术治疗晚期淋巴水肿。
J Surg Oncol. 2019 Mar;119(4):439-448. doi: 10.1002/jso.25360. Epub 2019 Jan 4.
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Correlation between Quantity of Transferred Lymph Nodes and Outcome in Vascularized Submental Lymph Node Flap Transfer for Lower Limb Lymphedema.带血管蒂颏下淋巴结皮瓣转移治疗下肢淋巴水肿中转移淋巴结数量与疗效的相关性
Plast Reconstr Surg. 2018 Oct;142(4):1056-1063. doi: 10.1097/PRS.0000000000004793.
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Anatomical Basis of the Gastroepiploic Vascularized Lymph Node Transfer: A Radiographic Evaluation Using Computed Tomographic Angiography.胃网膜血管化淋巴结转移的解剖学基础:使用计算机断层血管造影的影像学评估
Plast Reconstr Surg. 2018 Oct;142(4):1046-1052. doi: 10.1097/PRS.0000000000004772.
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The Diagnosis and Treatment of Peripheral Lymphedema: 2016 Consensus Document of the International Society of Lymphology.外周性淋巴水肿的诊断与治疗:国际淋巴学会2016年共识文件
Lymphology. 2016 Dec;49(4):170-84.
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Worldwide assessment of healthcare personnel dealing with lymphoedema.全球范围内对处理淋巴水肿的医护人员的评估。
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8
Vascularized Lymph Node Transfer for Lymphedema.用于淋巴水肿的带血管蒂淋巴结转移术
Semin Plast Surg. 2018 Feb;32(1):28-35. doi: 10.1055/s-0038-1632401. Epub 2018 Apr 9.
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Vascularized Jejunal Mesenteric Lymph Node Transfer: A Novel Surgical Treatment for Extremity Lymphedema.带血管蒂空肠系膜淋巴结转移术:一种治疗肢体淋巴水肿的新型外科手术方法
J Am Coll Surg. 2017 Nov;225(5):650-657. doi: 10.1016/j.jamcollsurg.2017.08.001. Epub 2017 Aug 14.
10
Lower Body Lymphedema in Patients with Gynecologic Cancer.妇科癌症患者的下肢淋巴水肿
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胃网膜血管化淋巴结转移治疗肢体淋巴水肿:中间植入与远端植入的比较

Gastroepiploic vascularized lymph node transfer for the treatment of extremity lymphedema: comparison between middle and distal inset.

作者信息

Manrique Oscar J, Bustos Samyd Said, Kapoor Trishul, Lin Jason, Ciudad Pedro, Forte Antonio J, Del Corral Gabriel, Mani Maria, Maruccia Michele, Terzic Andre

机构信息

Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, MN, USA.

Center for Regenerative Medicine, Mayo Clinic, Rochester, MN, USA.

出版信息

Gland Surg. 2020 Apr;9(2):528-538. doi: 10.21037/gs.2020.02.10.

DOI:10.21037/gs.2020.02.10
PMID:32420288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7225493/
Abstract

BACKGROUND

Middle and distal insets of gastroepiploic vascularized lymph node transfer (GE-VLNT) for extremity lymphedema have been described. However, there has been no prior comparison of surgical or patient-reported outcomes between these techniques. We analyzed the outcomes between both insets in patients with extremity lymphedema.

METHODS

Retrospective review of patients with extremity-lymphedema who underwent GE-VLNT. Two groups were analyzed: middle and distal recipient inset. We analyzed 6-month surgical and patient-reported outcomes using the Lymphedema Life Impact Scale-v2 (LLISv2) and scar satisfaction utilizing the Patient Scar Assessment Questionnaire (PSAQ).

RESULTS

Between 2017 and 2019, 26 patients with stage II unilateral extremity lymphedema underwent laparoscopically-harvested GE-VLNT (13 distal and 13 middle inset). There were no differences in patient demographics between groups. Mean hospital stay for patients with upper extremity lymphedema was 1.3 4.0 days (P<0.05), and for lower extremity lymphedema was 1.0 4.5 days (P<0.05), middle distal inset, respectively. Mean return to daily activities for patients with upper extremity lymphedema was 13.4 33.4 days (P<0.05), and for lower extremity lymphedema was 16.0 29.5 days (P<0.05), middle distal inset, respectively. Both middle and distal inset showed significant mean excess volume reduction at 6 months postoperatively for both upper and lower extremity lymphedema (upper extremity: middle inset 23.3%, distal inset: 22.0%; lower extremity: middle inset 23.3% and distal inset 13.3%). LLISv2 scores showed improved functional outcomes postoperatively in both upper and lower extremity lymphedema with both insets. Scar satisfaction with appearance and symptoms was higher with middle inset (P<0.05).

CONCLUSIONS

GE-VLNT is an effective surgical treatment for extremity lymphedema. The middle placement showed shorter hospital stay, early return to work and higher patient satisfaction.

摘要

背景

已描述了用于治疗肢体淋巴水肿的胃网膜血管化淋巴结转移术(GE-VLNT)的中、远端植入部位。然而,此前尚未对这些技术之间的手术或患者报告的结果进行比较。我们分析了肢体淋巴水肿患者两种植入部位的治疗结果。

方法

对接受GE-VLNT的肢体淋巴水肿患者进行回顾性研究。分析两组:中、远端受体植入部位。我们使用淋巴水肿生活影响量表v2(LLISv2)分析6个月时的手术和患者报告结果,并使用患者瘢痕评估问卷(PSAQ)分析瘢痕满意度。

结果

2017年至2019年期间,26例II期单侧肢体淋巴水肿患者接受了腹腔镜采集的GE-VLNT(13例远端植入和13例中间植入)。两组患者的人口统计学特征无差异。上肢淋巴水肿患者的平均住院时间为1.3±4.0天(P<0.05),下肢淋巴水肿患者为1.0±4.5天(P<0.