Kok G, Van de Wall B J M, Verleisdonk E J M M
UMC Utrecht, afd. Metabole Ziekten, Utrecht.
Contact: G. Kok (
Ned Tijdschr Geneeskd. 2020 May 18;164:D4122.
More and more patients with fractures are asking for bone growth stimulators. There are currently 2 types of bone growth stimulators on the market: stimulators using pulsed electromagnetic fields (PEMF) and stimulators using low-intensity pulsed ultrasound (LIPUS). There is insufficient evidence that LIPUS bone growth stimulator treatment is useful in patients with fresh fractures; the effects of LIPUS bone growth stimulation for delayed-union and non-union fractures need more in-depth investigation. There is also insufficient evidence that PEMF bone growth stimulation has beneficial effects on the healing of fresh fractures and delayed-union and non-union fractures. We do not recommend routine use of bone growth stimulators, partly because of the significant costs involved.
越来越多的骨折患者要求使用骨生长刺激器。目前市场上有两种类型的骨生长刺激器:使用脉冲电磁场(PEMF)的刺激器和使用低强度脉冲超声(LIPUS)的刺激器。目前尚无充分证据表明LIPUS骨生长刺激器治疗对新鲜骨折患者有用;LIPUS骨生长刺激对延迟愈合和不愈合骨折的效果需要更深入的研究。也没有充分证据表明PEMF骨生长刺激对新鲜骨折、延迟愈合和不愈合骨折的愈合有有益作用。我们不建议常规使用骨生长刺激器,部分原因是费用高昂。