,.
Invest Ophthalmol Vis Sci. 2020 May 11;61(5):27. doi: 10.1167/iovs.61.5.27.
To determine whether the blood flow in the superior retina is significantly different from that in the inferior retina, and to determine whether the posture affects the blood flow in the superior and inferior retina.
The blood flow in the vessels around the optic nerve head was measured by laser speckle flowgraphy in the sitting position in 68 healthy subjects. The blood flow in the superior peripapillary retina was compared with that in the inferior peripapillary retina. The measurements of the blood flow were performed in the sitting position, and the effect of switching to a supine position was determined at 2, 4, 6, 8, 10, and 30 minutes after the switch.
The total relative flow volume (RFV)-all, RFV-artery, and RFV-vein were significantly greater in the superior retina than in the inferior retina (all P < 0.001). The mean diameter-all and mean diameter-artery in the superior retina were significantly larger than that in the inferior retina (all P < 0.05). The mean blur rate (MBR)-all, MBR-artery, and MBR-vein in the superior retina were also greater than that in the inferior retina (P < 0.001, P < 0.01, and P < 0.001, respectively). Although the ocular perfusion pressure was significantly changed with the postural alteration, the total RFV-all remained greater in the superior retina than in the inferior retina after the postural change.
Clinicians need to be aware of the differences in the blood flow between the superior and inferior retinal peripapillary area when considering the mechanisms of retinochoroidal diseases.
确定视网膜上的血流量是否明显不同于视网膜下的血流量,以及确定姿势是否影响视网膜上、下的血流量。
通过激光散斑血流仪,在 68 名健康受试者的坐姿下测量视神经头周围血管的血流。比较视盘周围上、下视网膜的血流。在坐姿下进行血流测量,在切换后 2、4、6、8、10 和 30 分钟,确定切换到仰卧位的影响。
总相对血流容积(RFV)-全部、RFV-动脉和 RFV-静脉在视网膜上均明显大于视网膜下(均 P<0.001)。视网膜上的平均直径-全部和平均直径-动脉明显大于视网膜下(均 P<0.05)。视网膜上的平均模糊率(MBR)-全部、MBR-动脉和 MBR-静脉也大于视网膜下(均 P<0.001、P<0.01 和 P<0.001)。尽管姿势改变导致眼灌注压明显变化,但在姿势改变后,视网膜上的总 RFV-全部仍大于视网膜下。
临床医生在考虑视网膜脉络膜疾病的机制时,需要注意视盘周围上、下视网膜血流的差异。