Lao Bryan K, Kain Zeev N, Khoury Dina, Jenkins Brooke N, Prager Jeremy, Stevenson Robert S, Golianu Brenda, Zuk Jeannie, Gold Jeffrey I, Zhong Qiu, Fortier Michelle A
Department of Psychiatry & Behavioral Sciences, Duke University Hospital, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC, 27710, USA; UCI Center on Stress & Health, School of Medicine, University of California-Irvine, Irvine, CA, 505 S Main Street, Suite 940, Orange, CA, 92868, USA.
UCI Center on Stress & Health, School of Medicine, University of California-Irvine, Irvine, CA, 505 S Main Street, Suite 940, Orange, CA, 92868, USA; Department of Anesthesiology and Perioperative Care, University of California-Irvine, 333 City Blvd West, Orange, CA, 92868, USA; Child Study Center, Yale University School of Medicine, 230 S Frontage Rd, New Haven, CT, 06520, USA; American College of Perioperative Medicine, 15333 Culver Drive Suite 340-253, Irvine, CA, 92604, USA.
Int J Pediatr Otorhinolaryngol. 2020 Aug;135:110106. doi: 10.1016/j.ijporl.2020.110106. Epub 2020 May 11.
Using multiple well-validated measures and a large sample size, the goal of this paper was to describe the immediate clinical and behavioral recovery of children following tonsillectomy with or without an adenoidectomy (T&A) during the first two weeks following surgery.
Observational, longitudinal study.
Four major pediatric hospitals in the U.S. consisting of Children's Hospital of Orange County, Children's Hospital of Los Angeles, Lucile Packard Children's Hospital, and Children's Hospital Colorado.
and Methods: Participants included 827 patients between 2 and 15 years of age who underwent tonsillectomy with or without adenoidectomy surgery. Baseline and demographic information were gathered prior to surgery, and measures of clinical, behavioral, and physical recovery were recorded immediately following and up through two weeks after surgery.
Pain following T&A was clinically significant through the first post-operative week and nearly resolved by the end of the second week. Negative behavioral changes were highly prevalent after surgery (75.6% of children at Day 0) through the first week (63.9% at Week 1), and over 20% of children continued to evidence new onset negative behavioral changes at two weeks post-operatively. Children were rated as experiencing significant functional impairment in the immediate three days following surgery and most children returned to baseline functioning by the end of the second week.
Results of this study suggest that children show immediate impairment in functioning and experience clinically significant pain throughout the first week following T&A, and new onset maladaptive behavioral changes persisting even up to the two-week assessment period.
运用多种经过充分验证的测量方法并采用大样本量,本文旨在描述扁桃体切除术伴或不伴腺样体切除术(扁桃体腺样体切除术)后两周内儿童的即时临床和行为恢复情况。
观察性纵向研究。
美国四家主要的儿科医院,包括橙县儿童医院、洛杉矶儿童医院、露西尔·帕卡德儿童医院和科罗拉多儿童医院。
参与者包括827名2至15岁接受扁桃体切除术伴或不伴腺样体切除术的患者。术前收集基线和人口统计学信息,并在术后即刻及术后两周内记录临床、行为和身体恢复情况的测量结果。
扁桃体腺样体切除术后的疼痛在术后第一周具有临床显著性,到第二周结束时几乎消失。术后(术后第0天75.6%的儿童)至第一周(第1周63.9%)负面行为变化非常普遍,超过20%的儿童在术后两周仍有新出现的负面行为变化。术后即刻三天内儿童被评定为有显著功能损害,大多数儿童在第二周结束时恢复到基线功能水平。
本研究结果表明,儿童在扁桃体腺样体切除术后第一周内功能立即受损,经历临床显著性疼痛,甚至在长达两周的评估期内仍有新出现的适应不良行为变化。