Department of Surgery, Division of Transplant Surgery, University of Virginia, Charlottesville, VA, USA.
Division of HBP Surgery & Liver Transplantation, Department of Surgery, Korea University College of Medicine, Seoul, South Korea.
Int J Surg. 2020 Oct;82S:30-35. doi: 10.1016/j.ijsu.2020.05.024. Epub 2020 May 15.
The current supply of acceptable donor livers is not sufficient to meet the demands of listed patients awaiting transplantation resulting in thousands of deaths each year. Increased utilization of marginal livers may help alleviate this supply/demand mismatch by expanding the donor liver pool. The current status of liver transplantation using marginal donor grafts and efforts to optimize usage are discussed with attention to elderly donors, steatotic livers, donors after circulatory death, and split liver grafts.
目前可接受的供体肝脏供应不足以满足等待移植的患者的需求,导致每年都有数千人死亡。增加边缘供肝的利用率可以通过扩大供肝池来帮助缓解这种供需不匹配的情况。本文讨论了使用边缘供体移植物进行肝移植的现状以及优化使用的努力,特别关注老年供体、脂肪肝、循环死亡后供体和劈裂肝移植。