Division of Infectious Diseases, Jichi Medical University Hospital, Tochigi, Japan, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Division of Infectious Diseases, Jichi Medical University Hospital, Tochigi, Japan, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan; Department of Infection and Immunity, School of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
J Infect Chemother. 2020 Aug;26(8):780-784. doi: 10.1016/j.jiac.2020.03.003. Epub 2020 May 15.
Several studies across various countries have shown the benefit of infectious disease consultation in patients with Staphylococcus aureus bacteremia (SAB). However, the effect of such consultation services in patients with SAB in Japan remains unknown. Accordingly, we aimed to examine the effectiveness of infectious disease consultation in SAB patients at an accredited hospital in Japan. We hypothesized that infectious disease consultation in SAB patients is associated with lower in-hospital mortality. We identified patients with SAB between January 2011 and January 2014. SAB was defined as the presence of at least one set of positive blood culture samples. The outcomes of patients who did and did not receive bedside infectious disease consultation were compared. The primary outcome was in-hospital mortality. We identified 183 patients with SAB. Eighty-seven patients (48%) received infectious disease consultation services, while 96 (52%) did not. There were no significant differences in in-hospital mortality between the infectious disease consultation and control groups (15.0% vs. 23.0%, p = 0.20). Logistic regression analysis showed that bedside infectious disease consultation (odds ratio, 0.23; 95% confidence interval, 0.08-0.69; p = 0.01) was independently associated with lower in-hospital mortality. In conclusion, bedside infectious disease consultation may help reduce the in-hospital mortality in patients with SAB in Japan.
许多国家的研究表明，传染病咨询对金黄色葡萄球菌菌血症（SAB）患者有益。然而，日本 SAB 患者的此类咨询服务的效果尚不清楚。因此，我们旨在研究日本认证医院中 SAB 患者的传染病咨询的有效性。我们假设 SAB 患者的传染病咨询与住院死亡率降低有关。我们确定了 2011 年 1 月至 2014 年 1 月之间患有 SAB 的患者。SAB 的定义是至少有一组阳性血培养样本。比较了接受和未接受床边传染病咨询的患者的结局。主要结局是住院死亡率。我们确定了 183 例 SAB 患者。87 例（48％）患者接受了传染病咨询服务，而 96 例（52％）患者未接受。传染病咨询组和对照组的住院死亡率无显着差异（15.0％与 23.0％，p = 0.20）。逻辑回归分析表明，床边传染病咨询（优势比，0.23；95％置信区间，0.08-0.69；p = 0.01）与较低的住院死亡率独立相关。总之，床边传染病咨询可能有助于降低日本 SAB 患者的住院死亡率。
