Pediatric Diagnostic Center, 300 Hillmont Avenue, Building 340, Suite 302, Ventura, CA 93003, USA.
Division of Physician Assistant Studies, Department of Human Performance and Applied Exercise Science, West Virginia University School of Medicine, 1 Medical Center Drive, PO Box 9226, Morgantown, WV 26506-9226, USA.
Prim Care. 2020 Jun;47(2):189-216. doi: 10.1016/j.pop.2020.02.001. Epub 2020 Feb 12.
Evaluation of the child with abnormal pubertal development can be challenging for the primary care provider. Understanding the factors associated with timing of pubertal onset and the normal sequence of pubertal changes is useful in evaluation of children with puberty disorders. A thorough workup includes assessment of growth rate, Tanner staging, and rate of pubertal progression, in addition to an extensive history and physical examination to identify signs and symptoms of disorders associated with abnormal pubertal timing. Initial diagnostic studies will most often include a bone age, levels of gonadotropins, and levels of estradiol (for girls) or testosterone (for boys).
评估青春期发育异常的儿童对于初级保健医生来说可能具有挑战性。了解与青春期开始时间和青春期变化正常顺序相关的因素，对于评估青春期障碍的儿童很有用。全面的检查包括评估生长速度、Tanner 分期和青春期进展速度，以及详细的病史和身体检查，以识别与青春期时间异常相关的疾病的体征和症状。最初的诊断研究通常包括骨龄、促性腺激素水平以及雌二醇（女孩）或睾酮（男孩）水平。
