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一名颈髓损伤伴低血压个体的动脉功能不全性溃疡。

An arterial insufficiency ulcer in an individual with cervical spinal cord injury and hypotension.

机构信息

Sidney Kimmel Medical College of Thomas Jefferson University, 1100 Walnut Street, Suite 601, Philadelphia, PA, 19107, USA.

出版信息

Spinal Cord Ser Cases. 2020 May 18;6(1):42. doi: 10.1038/s41394-020-0291-8.

Abstract

INTRODUCTION

Arterial ulcers develop as a complication of tissue hypoperfusion, ordinarily from atherosclerotic disease, but sometimes due to other medical conditions or trauma. While people with spinal cord injury (SCI) may be predisposed to resting hypotension, and, hence, to inadequate peripheral circulation, there are no reports of arterial ulcers as a secondary effect of SCI.

CASE PRESENTATION

A 54-year-old woman with long standing cervical SCI presented with a nonhealing lateral malleolar ulcer that was complicated by osteomyelitis and unresponsive to biweekly debridement. On examination, she was hypotensive with cool extremities and non-palpable pedal pulses but had no evidence of atherosclerotic disease, cardio-metabolic derangement, or vasculopathy. We treated her with Midodrine with improvement in her peripheral circulation then referred her for surgical intervention.

DISCUSSION

To our knowledge, this is the first reported case of an arterial ulcer in a person living with SCI that was most likely caused by resting hypotension. It is possible that individuals with SCI-particularly those with higher-level injuries-are at risk for this condition. Clinicians must be alert to arterial ulcers as a potential complication of SCI with concomitant hypotension.

摘要

简介

动脉溃疡是组织灌注不足的并发症,通常由动脉粥样硬化疾病引起,但有时也与其他医疗状况或创伤有关。尽管脊髓损伤(SCI)患者可能容易出现静息性低血压,从而导致外周循环不足,但尚无 SCI 作为继发效应导致动脉溃疡的报道。

病例介绍

一位 54 岁女性患有长期的颈段 SCI,出现无法愈合的外踝溃疡,并发骨髓炎,且每两周进行一次清创术也无反应。检查时,她血压低,四肢发凉,足背动脉搏动不可触及,但没有动脉粥样硬化疾病、心血管代谢紊乱或血管病变的证据。我们用米多君治疗她的周围循环,随后转介她进行手术干预。

讨论

据我们所知,这是首例报道的 SCI 患者发生动脉溃疡的病例,很可能是由静息性低血压引起的。可能患有 SCI 的人,尤其是高水平损伤的人,有发生这种情况的风险。临床医生必须警惕动脉溃疡作为并发低血压的 SCI 的潜在并发症。

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