Division of Psychiatry, University College London, Maple House, 6th floor, 149 Tottenham Court Road, London, W1T 7NF, UK.
Department of Primary Care and Population Health, University College London, UCL Medical School (Royal Free Campus), Upper Third Floor, Rowland Hill Street, London, NW3 2PF, UK.
Soc Psychiatry Psychiatr Epidemiol. 2020 Dec;55(12):1659-1669. doi: 10.1007/s00127-020-01879-9. Epub 2020 May 18.
People with severe mental illnesses (SMI) have an increased risk of cardiovascular disease (CVD). Research in the general population suggests that social support may protect against increased CVD morbidity and mortality; however, this may not apply to those with SMI. We aimed to explore the association between perceived social support and attendance at primary care nurse CVD risk reduction clinic appointments and CVD risk-reducing behaviours in an SMI population with elevated CVD risk factors.
We used longitudinal and cross-sectional data from a randomised controlled trial on 326 adults with SMI recruited via 76 general practices in England. Multilevel regression analysis estimated the effect of perceived social support on attendance at CVD risk reduction clinic appointments over 6 months, and adherence to CVD medication, physical activity, diet, smoking and alcohol use at baseline, adjusted by age, sex, ethnicity, deprivation, psychiatric diagnosis and employment.
Perceived social support predicted greater appointment attendance in unadjusted (IRR = 1.005; 1.000-1.010; p = 0.05) but not adjusted analysis (IRR = 1.003; 0.998-1.009; p = 0.25). Perceived social support was associated with greater adherence to medication; for each 1% increase in social support, there was a 4.2% increase in medication adherence (OR = 1.042; 1.015-1.070; p = 0.002). No association was found between greater perceived social support and greater physical activity, lower sedentary behaviour, healthier diet, lower alcohol use or being a non-smoker.
Social support may be an important facilitator for CVD medication adherence and is potentially important for primary care appointment attendance; however, alternative strategies might be needed to help people with SMI engage in physical activity, healthier diets and to reduce their smoking and alcohol use.
患有严重精神疾病(SMI)的人患心血管疾病(CVD)的风险增加。一般人群的研究表明,社会支持可能有助于降低 CVD 的发病率和死亡率;然而,这可能不适用于患有 SMI 的人群。我们旨在探讨感知社会支持与 SMI 人群初级保健护士 CVD 风险降低诊所预约和 CVD 风险降低行为之间的关系,这些人群具有升高的 CVD 危险因素。
我们使用了一项针对英格兰 76 家普通诊所招募的 326 名 SMI 成年人的随机对照试验的纵向和横断面数据。多层次回归分析估计了感知社会支持对 6 个月内 CVD 风险降低诊所预约的影响,以及在基线时对 CVD 药物、体育活动、饮食、吸烟和饮酒的依从性,调整因素包括年龄、性别、种族、贫困程度、精神诊断和就业状况。
在未调整分析中,感知社会支持预测了更高的预约出勤率(IRR=1.005;1.000-1.010;p=0.05),但在调整分析中则没有(IRR=1.003;0.998-1.009;p=0.25)。感知社会支持与药物治疗的更高依从性相关;社会支持每增加 1%,药物依从性就会增加 4.2%(OR=1.042;1.015-1.070;p=0.002)。在感知社会支持与更高的体力活动、更低的久坐行为、更健康的饮食、更低的饮酒量或不吸烟之间,没有发现关联。
社会支持可能是 CVD 药物治疗依从性的一个重要促进因素,对初级保健预约出勤率也很重要;然而,可能需要其他策略来帮助 SMI 患者参与体力活动、更健康的饮食以及减少吸烟和饮酒。