Dalgarno B G, Brown R M, Pickford C J
Environmental and Medical Sciences Division, Harwell Laboratory, Oxfordshire, UK.
Biomed Environ Mass Spectrom. 1988 Oct;16(1-12):377-80. doi: 10.1002/bms.1200160174.
A new inorganic mass spectrometric technique is described which allows sensitive, rapid and economic determination of trace element concentrations and isotope ratios in aqueous samples. This paper illustrates the potential of the technique in one particular application area, namely the measurement of strontium isotope ratios in human blood and urine following ingestion of an enriched stable strontium isotope. The data from a human volunteer experiment illustrate the viability of the analytical method, with measurement precisions of +/- 0.2% (1 sigma) achieved for the isotope ratio in urine samples, which contained approximately 300 ng 86Sr in the volume required for analysis. Measurement precision is limited by counting statistics.
本文描述了一种新的无机质谱技术，该技术能够灵敏、快速且经济地测定水性样品中的微量元素浓度和同位素比率。本文阐述了该技术在一个特定应用领域的潜力，即摄入富集稳定锶同位素后，测量人体血液和尿液中的锶同位素比率。一项人体志愿者实验的数据证明了该分析方法的可行性，尿液样品中同位素比率的测量精度达到了±0.2%（1σ），分析所需体积的尿液样品中约含有300 ng 86Sr。测量精度受计数统计的限制。
