用于诊断妊娠期糖尿病的口服葡萄糖耐量试验的两个标准。
Two criteria of oral glucose tolerance test to diagnose gestational diabetes mellitus.
作者信息
Nunes Rodrigo Dias, Flôres Mayara Eloisa, Seemann Mayara, Traebert Eliane, Traebert Jefferson
机构信息
. Escola de Medicina. Universidade do Sul de Santa Catarina, Palhoça, SC, Brasil.
. Programa de Pós Graduação em Ciência da Saúde. Universidade do Sul de Santa Catarina, Palhoça, SC, Brasil.
出版信息
Rev Assoc Med Bras (1992). 2020 May 15;66(2):139-145. doi: 10.1590/1806-9282.66.2.139.
OBJECTIVE
To evaluate two different criteria, one or two cut-off values, of oral glucose tolerance test with 75g of glucose for the diagnosis of gestational diabetes mellitus.
METHODS
A cross-sectional study involving 120 records of pregnant women who received prenatal care at the service of a Brazilian university was carried out. Bivariate analysis of obstetric and perinatal outcomes was performed using the chi-square test.
RESULTS
Considering criterion I, 12.5% of patients were diagnosed with gestational diabetes mellitus. Patients were 3.57 times more likely to have a large fetus for the gestational age at birth (p=0.038). Using criterion II, gestational diabetes mellitus was diagnosed in 5.8% of patients, macrosomia was 7.73 times more likely to be found in the presence of gestational diabetes mellitus (p=0.004), and a large fetus for the gestational age at birth was 8.17 times more likely (p=0.004).
CONCLUSIONS
There was a difference in the prevalence of gestational diabetes mellitus between the two criteria analyzed. The new criterion proposed increased prevalence.
目的
评估采用75克葡萄糖口服葡萄糖耐量试验诊断妊娠期糖尿病的两种不同标准（一个或两个临界值）。
方法
开展一项横断面研究，纳入了巴西一所大学医疗服务机构中120例接受产前检查的孕妇记录。采用卡方检验对产科和围产期结局进行双变量分析。
结果
按照标准I，12.5%的患者被诊断为妊娠期糖尿病。这些患者出生时出现大于胎龄儿的可能性是其他患者的3.57倍（p = 0.038）。按照标准II，5.8%的患者被诊断为妊娠期糖尿病，妊娠期糖尿病患者出现巨大儿的可能性是无妊娠期糖尿病患者的7.73倍（p = 0.004），出生时大于胎龄儿的可能性是其他患者的8.17倍（p = 0.004）。
结论
所分析的两种标准在妊娠期糖尿病患病率方面存在差异。所提出的新标准使患病率增加。
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