Antimicrobial prophylaxis of contaminated tissues containing suture implants.

Rodeheaver G, Edgerton M T, Smith S, King H, Kurtz L, Edlich R

Am J Surg. 1977 May;133(5):609-11. doi: 10.1016/0002-9610(77)90021-6.

Neomycin sulfate was the only antibiotic tested that significantly reduced the incidence of infections around suture implant sites. The therapeutic efficacy of this antibiotic was related to the chemical and physical configuration of the sutures.