Scher K S, Jones C W, Wroczynski A F
Surg Gynecol Obstet. 1984 Feb;158(2):117-9.
An experimental wound infection model was used to compare the effectiveness of topical and systemic cefazolin in the prevention of wound infection. Studies were conducted using both Staphylococcus aureus and Escherichia coli as the contaminating organisms. Regardless of the wound pathogen studied, there were no significant differences between topical and systemic cefazolin with regard to wound bacterial concentrations and the incidence of wound infection.
采用实验性伤口感染模型比较局部和全身应用头孢唑林预防伤口感染的效果。研究中使用金黄色葡萄球菌和大肠杆菌作为污染菌。无论研究的伤口病原体如何，局部和全身应用头孢唑林在伤口细菌浓度和伤口感染发生率方面均无显著差异。
