Mazzawi Tarek, Chaiyapo Auamduan, Kongkam Pradermchai, Ridtitid Wiriyaporn, Rerknimitr Rungsun
Section of Gastroenterology, Department of Medicine, Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Gastrointestinal Endoscopy Excellence Center and Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Pancreas Research Unit, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Gastrointestinal Endoscopy Excellence Center and Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; Pancreas Research Unit, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Department of Surgery, Prapokklao Hospital, Chanthaburi, Thailand.
Arab J Gastroenterol. 2020 Jun;21(2):128-131. doi: 10.1016/j.ajg.2020.04.014. Epub 2020 May 16.
Patients presenting with pancreatic ductal adenocarcinoma in an advanced inoperable stage receive chemoradiotherapy. Endoscopic ultrasound guided radiofrequency ablation (EUS-RFA) has been proposed as a new therapeutic option for these patients alongside chemotherapy. The evaluation of treatment response is mainly based on radiological evaluation of the changes in tumour size. Unfortunately, the currently available radiological methods cannot clearly differentiate between necrotic tissue and viable tumour. EUS elastography is an ultrasound technique that can grade the hardness of a lesion and classify it as benign, inflammatory or neoplastic as previously reported. This case report of 2 patients shows that using EUS elastography is beneficial in characterizing the nature of the changes occurring to the tumour mass following EUS-RFA of pancreatic tumour.
处于晚期无法手术阶段的胰腺导管腺癌患者接受放化疗。内镜超声引导下射频消融术（EUS-RFA）已被提议作为这些患者化疗之外的一种新治疗选择。治疗反应的评估主要基于对肿瘤大小变化的影像学评估。不幸的是，目前可用的影像学方法无法清楚区分坏死组织和存活肿瘤。如先前报道，EUS弹性成像术是一种超声技术，可对病变硬度进行分级并将其分类为良性、炎性或肿瘤性。这例2名患者的病例报告表明，使用EUS弹性成像术有助于明确胰腺肿瘤EUS-RFA后肿瘤块发生变化的性质。
