Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
Sackler School of Medicine at Tel Aviv University, Tel Aviv, Israel.
J Craniofac Surg. 2020 Sep;31(6):e569-e572. doi: 10.1097/SCS.0000000000006547.
The application of dexmedetomidine (precedex) in pediatric settings has increased due to its superior safety and efficacy profile and it has been specifically suggested as an adjunct to IV acetaminophen and a substitute for morphine in craniosynostosis repair. However, reports of its use in pediatrics, let alone in craniosynostosis repair, remain limited and to date there are no studies addressing its use after craniosynostosis repair in children. This study is an IRB-approved retrospective case review of the use of dexmedetomidine following pediatric craniosynostosis repair as a postoperative analgesic/sedative agent at one institution.
右美托咪定（precedex）在儿科领域的应用因其优越的安全性和疗效而增加，并且已被特别建议作为 IV 对乙酰氨基酚的辅助药物，以及在颅缝早闭修复中替代吗啡。然而，其在儿科中的应用报告，更不用说在颅缝早闭修复中的应用，仍然有限，迄今为止，尚无研究探讨其在儿童颅缝早闭修复后的应用。本研究是对一家机构中右美托咪定在小儿颅缝早闭修复后作为术后镇痛/镇静剂使用的情况进行的一项经过机构审查委员会批准的回顾性病例研究。
