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评估外科重症监护病房老年患者的谵妄结局。

Evaluating delirium outcomes among older adults in the surgical intensive care unit.

机构信息

School of Nursing, Northeastern University, 360 Huntington Ave, Robinson Hall, Boston, MA 02115, United States.

Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, United States.

出版信息

Heart Lung. 2020 Sep-Oct;49(5):578-584. doi: 10.1016/j.hrtlng.2020.04.009. Epub 2020 May 17.

Abstract

BACKGROUND

Delirium is prevalent in hospitalized older adults. Little is known about delirium among older adults admitted to the surgical intensive care unit (SICU).

OBJECTIVES

The purpose of this study was to describe the incidence of delirium, length of stay, 30-day readmission and mortality rates experienced by older adults in the SICU before and after a nurse-driven protocol for delirium-informed care.

METHODS

This study employed a retrospective observational cohort design. Consecutive patients 65 years or older admitted to the SICU over six-month periods were compared before (n = 101) and following (n = 172) a nurse-driven protocol for delirium-informed care. Patient-level outcomes included incidence delirium, SICU and hospital length of stay, 30-day readmission and mortality rates. All measures were collected using medical record review.

RESULTS

In the pre- and post-intervention cohorts, 37% (37/101) and 33% (56/172) of patients screened positive for delirium, respectively. Following implementation of the delirium-informed care intervention, the number of days where no CAM-ICU assessment was performed significantly decreased (Pre 1.1 ± 1.4; Post 0.45 ± 0.65; p <0.001) and the number of negative assessments significantly increased (Pre 2.45 ± 1.66; Post 2.94 ± 1.69; p < 0.0178), indicating that nurses post-intervention were more consistently assessing for delirium.

CONCLUSIONS

This study failed to show improvements in patient outcomes (SICU and hospital length of stay, 30-day readmission and mortality rates), before and following a delirium-informed care intervention. However, positive trends in the data suggest that delirium-informed care has the potential to increase rates of assessment and delirium identification, thereby providing the foundation for reducing the consequences of delirium and improve patient-level outcomes. Further better controlled prospective work is needed to validate this intervention.

摘要

背景

谵妄在住院老年患者中较为普遍。然而,对于入住外科重症监护病房(SICU)的老年患者的谵妄情况,我们知之甚少。

目的

本研究旨在描述在实施护士主导的谵妄知情护理方案前后,入住 SICU 的老年患者发生谵妄的发生率、住院时间、30 天再入院率和死亡率。

方法

本研究采用回顾性观察队列设计。比较了在 6 个月的时间内连续入住 SICU 的 65 岁及以上的患者,一组为实施护士主导的谵妄知情护理方案前(n=101),另一组为实施后(n=172)。患者水平的结局包括谵妄发生率、SICU 和医院住院时间、30 天再入院率和死亡率。所有措施均通过病历回顾收集。

结果

在干预前和干预后队列中,分别有 37%(37/101)和 33%(56/172)的患者筛查出谵妄阳性。在实施谵妄知情护理干预后,未进行 CAM-ICU 评估的天数明显减少(干预前 1.1±1.4 天;干预后 0.45±0.65 天;p<0.001),而阴性评估的天数明显增加(干预前 2.45±1.66 天;干预后 2.94±1.69 天;p<0.0178),这表明护士在干预后更一致地进行了谵妄评估。

结论

本研究未能显示在实施谵妄知情护理干预前后,患者结局(SICU 和医院住院时间、30 天再入院率和死亡率)得到改善。然而,数据中的积极趋势表明,谵妄知情护理有可能增加评估和谵妄识别的比例,从而为减少谵妄的后果和改善患者水平的结局奠定基础。需要进一步开展更好的前瞻性对照研究来验证该干预措施。

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